Management of Severe Food Allergies in Children
Immediately prescribe an epinephrine autoinjector with hands-on training for any child with suspected severe food allergy, even before diagnostic confirmation, as this is potentially lifesaving while awaiting allergist evaluation. 1
Immediate Actions in Primary Care
Emergency Medication Prescription
- Prescribe epinephrine autoinjector immediately upon suspicion of severe food allergy, regardless of diagnostic certainty, as children wait an average of 4 months for allergist consultation and remain at risk for life-threatening reactions during this period 1
- Provide hands-on training to caregivers and age-appropriate children on proper epinephrine administration technique 1
- Prescribe antihistamines as adjunctive therapy for managing non-severe allergic symptoms 1
- Epinephrine remains the only medication proven effective for treating acute systemic allergic reactions and anaphylaxis 1
Immediate Dietary Management
- Instruct complete avoidance of the suspected food allergen until allergist evaluation confirms or refutes the diagnosis 1, 2
- Educate families on reading food labels and recognizing hidden sources of allergens 1
- Warn about precautionary labeling (e.g., "may contain traces") and advise strict avoidance of such products due to real contamination risk 1
Comprehensive Family Education
Recognition of Anaphylaxis
Train caregivers to recognize signs and symptoms of anaphylaxis, which may include: 1
- Skin: hives, flushing, angioedema
- Respiratory: wheezing, throat tightness, difficulty breathing
- Gastrointestinal: vomiting, abdominal pain (especially within 2-3 hours of exposure)
- Cardiovascular: dizziness, loss of consciousness
Emergency Action Plan
- Create a written food allergy emergency action plan that specifies when and how to administer epinephrine 1, 2
- Ensure caregivers understand that epinephrine should be given at first sign of systemic reaction, without waiting for symptom progression 1
- Provide school documentation including emergency action plans, Section 504 plans, or individualized education plans (IEPs) as needed 1, 2
Allergist Referral (Essential Component)
Timing and Purpose
- Refer all children with suspected severe food allergy to an allergist for definitive diagnostic testing 1, 2
- The allergist will perform oral food challenges when necessary to verify clinical relevance of positive tests, as the double-blind, placebo-controlled food challenge remains the diagnostic gold standard 1
- Allergist evaluation is critical because positive IgE testing alone has poor positive predictive value and does not confirm true clinical allergy 2, 3
What the Allergist Provides
- Detailed clinical history correlation with test results 2
- Additional diagnostic testing including specific IgE measurements and supervised oral food challenges in controlled settings 2
- Formulation of comprehensive emergency anaphylaxis action plan 1, 2
- Education on cross-reactivity risks (e.g., between peanuts and tree nuts) 1
- Facilitation of dialogue with schools and childcare centers 1
Nutritional Monitoring
Growth and Development
- Arrange nutritional counseling for all children with confirmed food allergies to ensure elimination diets provide adequate nutrients 1, 3
- Monitor growth parameters regularly, as avoidance diets can lead to nutritional deficiencies if not properly managed 1, 3
- Carefully planned allergen-free diets can maintain healthy, active lifestyles when properly supervised 1
Long-Term Follow-Up Strategy
Ongoing Management
- Schedule yearly follow-up for retesting, as many childhood food allergies (particularly milk and egg) resolve over time 2, 3
- Co-manage with the allergist rather than transferring care entirely, maintaining awareness of the child's special needs 1
- Address quality-of-life issues, as food allergy significantly increases anxiety and diminishes quality of life for patients and families 1
- Ensure families regularly check expiration dates on emergency medications and replace as needed 2
Adolescent Transition
- As children transition into adolescence, provide age-appropriate counseling on strategies for avoiding allergens in various social settings 1
- Emphasize increasing personal responsibility for food selection and emergency medication carrying 1
Critical Pitfalls to Avoid
Common Errors
- Never rely solely on positive IgE testing without clinical history, as sensitization does not equal clinical allergy 2, 3
- Do not implement unnecessary dietary restrictions in children without documented food allergy, particularly for managing atopic dermatitis, asthma, or eosinophilic esophagitis 1, 3
- Never delay epinephrine prescription while awaiting allergist consultation, as this leaves children vulnerable to potentially fatal reactions 1
- Avoid using allergy testing to "predict future risk"—testing should only evaluate reactions that have already occurred 3
Special Vaccine Considerations
- MMR vaccine is safe for children with egg allergy, even those with severe reactions 1
- Influenza vaccines are not recommended for patients with history of severe egg reactions (hives, angioedema, allergic asthma, or anaphylaxis to egg proteins) 1
- Yellow fever vaccine should not be administered to patients with severe egg allergy without allergy evaluation and vaccine testing 1
Emerging Therapies (Not Yet Standard Practice)
- Oral immunotherapy (OIT) and sublingual immunotherapy (SLIT) are under investigation for inducing clinical desensitization 1
- These approaches carry risk of severe reactions and are not recommended for routine clinical practice at this time 1
- Allergen-specific immunotherapy with cross-reactive allergens is not recommended for treating IgE-mediated food allergy 1