From the Research
Waiting Period for Testing Protein S Deficiency after Discontinuing Xarelto (Rivaroxaban)
- There is no specific waiting period recommended in the provided studies for testing Protein S deficiency after discontinuing Xarelto (rivaroxaban) 1, 2, 3, 4, 5.
- However, it is essential to note that rivaroxaban can falsely elevate functional protein S activity, which may lead to a missed diagnosis of protein S deficiency if testing relies solely on protein S activity assays 1.
- Free protein S antigen testing is recommended in patients taking rivaroxaban to exclude hereditary protein S deficiency 1.
- The provided studies focus on the treatment of patients with protein S deficiency using rivaroxaban and do not provide guidance on the waiting period for testing after discontinuing the medication 2, 3, 4, 5.
- Clinicians should consider the potential effects of rivaroxaban on protein S activity and antigen levels when interpreting test results and deciding on the timing of testing after discontinuing the medication 1.