Is Gestational Age Always Older Than Embryonic Age?
Yes, gestational age is always approximately 2 weeks older than embryonic age because gestational age is calculated from the first day of the last menstrual period, which occurs roughly 2 weeks before ovulation and fertilization. 1
Understanding the Terminology
Gestational age (GA) refers to the duration of pregnancy measured from the first day of the last menstrual period (LMP), expressed in completed weeks and days. 2 This is the standard convention used in obstetrics for dating pregnancies and timing clinical interventions. 2
Embryonic age (also called "conceptual age" or "fetal age") measures the actual time since fertilization/conception, which typically occurs at ovulation—approximately 14 days after the start of the last menstrual period. 2, 1
The Mathematical Relationship
- Gestational age = Embryonic age + 2 weeks (approximately) 1
- The embryonic period of 4-8 weeks post-ovulation corresponds to 6-10 weeks gestational age from LMP 1
- This 2-week difference is built into the dating system and remains constant throughout pregnancy 1
Clinical Implications
The distinction matters most during organogenesis:
- Organogenesis occurs at embryonic age 4-8 weeks, which equals 6-10 weeks GA—this represents the period of highest teratogenic risk 1
- The embryonic period extends until 10 weeks 6 days GA, after which the conceptus becomes a fetus at 11 weeks 0 days GA 2, 1
Important Caveats
In assisted reproductive technology (ART) pregnancies, the calculation differs because the exact fertilization date is known:
- For day 5 blastocyst transfers, add 19 days to the transfer date to calculate gestational age 3
- This provides superior accuracy compared to LMP-based dating 3
The assumption of a 28-day cycle with day 14 ovulation may not apply to all women, which can introduce errors in LMP-based dating. 4 Women with longer menstrual cycles may have their gestational age overestimated by the LMP method, leading to misclassification of postterm deliveries. 4
First-trimester ultrasound (crown-rump length measurement) provides more accurate gestational age estimation than LMP dating, with accuracy within ±5-7 days, and should be used to adjust the estimated due date when discrepancies exceed 5 days. 5