Assessment of Testicular Atrophy Risk
Based on your hormone profile and sperm count, you do NOT have testicular atrophy—your testosterone is normal-high (52 nmol/L), your sperm count is excellent (60 million/ml, well above the 16 million/ml WHO threshold), and while your FSH of 10.0 IU/L is mildly elevated, this does not indicate testicular failure when sperm production is clearly preserved. 1, 2
Understanding Your Hormone Profile
Your results show a pattern consistent with mild compensatory elevation of FSH with preserved testicular function, not primary testicular failure:
- FSH 10.0 IU/L is mildly elevated above the 7.6 IU/L threshold, indicating your pituitary is working slightly harder to maintain sperm production, but this does NOT mean testicular atrophy when actual sperm production is normal 1, 2
- LH 7.0 IU/L is normal, arguing strongly against primary testicular failure (which would show markedly elevated LH alongside elevated FSH) 1, 2
- Testosterone 52 nmol/L is in the high-normal to elevated range, confirming your Leydig cells (testosterone-producing cells) are functioning well 1
- Sperm count 60 million/ml is nearly 4 times higher than the WHO lower reference limit of 16 million/ml, definitively proving your testes are producing sperm normally 1
Critical Point About FSH Interpretation
FSH >7.6 IU/L is associated with testicular dysfunction ONLY when accompanied by testicular atrophy on examination AND absent or severely reduced sperm production (<5 million/ml). 1, 2 Your situation is completely different:
- FSH levels between 7.6-10 IU/L typically indicate some degree of impaired spermatogenic efficiency, but NOT complete testicular failure 2
- Up to 50% of men with non-obstructive azoospermia (zero sperm) and elevated FSH still have retrievable sperm, so your FSH of 10.0 with 60 million sperm/ml is entirely consistent with maintained fertility 1, 2
- FSH alone cannot predict fertility status—your actual sperm count is the definitive evidence that your testes are functioning 1, 2
Addressing the 9ml Ultrasound Finding
The ultrasound measurement of 9ml bilaterally is almost certainly a technical measurement error, and here's why:
- Testicular volumes <12ml are definitively considered atrophic and strongly correlate with impaired spermatogenesis, reduced sperm counts, and elevated FSH 3
- If your testes were truly 9ml bilaterally, you would NOT have a sperm count of 60 million/ml—testicular volume strongly correlates with total sperm count and sperm concentration 3, 4
- The most common ultrasound measurement error is incorrect width measurement (measuring obliquely rather than at true maximum width), which systematically underestimates volume by 20-30% 3
- Using the wrong formula (0.52 ellipsoid coefficient instead of the correct 0.71 Lambert coefficient) also systematically underestimates volume 3
What You Should Do About the Ultrasound
Request a repeat scrotal ultrasound with explicit attention to proper measurement technique, specifying: 3
- Use high-frequency probes (>10 MHz) for maximum resolution
- Measure three perpendicular dimensions (length, width, height) on axial slices
- Calculate volume using the Lambert formula: Length × Width × Height × 0.71
- Compare measurements to the contralateral testis (size discrepancy >2ml or 20% warrants further evaluation)
Clinical Significance of Your Results
Your combination of mildly elevated FSH with normal LH, adequate testosterone, and excellent sperm count is the classic pattern seen in oligospermia or normal fertility with slightly reduced spermatogenic efficiency—NOT testicular atrophy. 1
- Normal LH levels argue against primary testicular failure 1
- High-normal testosterone makes primary testicular failure extremely unlikely 1
- Sperm count of 60 million/ml with total motile sperm count likely >30 million places you well within the normal fertile range 1
What This Means for Your Fertility
You have excellent fertility potential based on these parameters:
- Your sperm concentration exceeds WHO reference limits by nearly 4-fold 1
- Natural conception rates are excellent with sperm counts in your range 1
- The mildly elevated FSH does NOT preclude normal fertility when sperm production is clearly preserved 1, 2
Important Actions to Protect Your Fertility
Never use exogenous testosterone or anabolic steroids—these will completely suppress spermatogenesis through negative feedback, potentially causing azoospermia that takes months to years to recover 1, 2
Optimize modifiable factors:
- Smoking cessation 1
- Maintain healthy body weight (BMI <25) 1
- Minimize heat exposure to the testes 1
- Avoid gonadotoxic medications when possible 1
Recommended Follow-Up
Given the discrepancy between your excellent sperm count and the questionable ultrasound measurement:
- Repeat scrotal ultrasound with proper technique to obtain accurate testicular volume measurements 3
- Repeat semen analysis in 3-6 months to confirm stability of sperm parameters 1
- Physical examination by a urologist to assess testicular consistency, presence of varicocele, and vas deferens/epididymal abnormalities 1
- Complete hormonal panel including measurement of SHBG to calculate free testosterone, as this provides additional context for your mildly elevated FSH 1
The bottom line: Your hormone profile and sperm count indicate normal testicular function with mild compensatory FSH elevation, NOT testicular atrophy. The 9ml ultrasound measurement is inconsistent with your excellent sperm production and likely represents technical measurement error.