What does a high RAGE (Revised Acute Physiology and Chronic Health Evaluation) score indicate in geriatric assessment for elderly patients?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: January 21, 2026View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

What is a High RAGE Score in Geriatrics Assessment?

There is no validated geriatric assessment tool called "RAGE score" in the medical literature or clinical guidelines. You may be confusing this with other established geriatric assessment tools that are actually used in clinical practice.

Commonly Used Geriatric Assessment Scores (Not RAGE)

Geriatric Assessment Tools That Actually Exist

The most likely tools you may be referring to include:

  • CRASH Score (Chemotherapy Risk Assessment Scale for High-Age Patients): Predicts risk of hematologic and nonhematologic chemotherapy toxicity in patients ≥70 years by integrating functional status, nutrition, and cognition from geriatric assessment domains 1

  • CARG Score: Provides specific estimates on risk of chemotherapy toxicity in older cancer patients receiving chemotherapy 1

  • GTOS (Geriatric Trauma Outcome Score): Calculated as [age] + [2.5 × ISS] + 22 (if packed red blood cells transfused ≤24 hours), with area under the curve of 0.82 for predicting in-hospital mortality in trauma patients >65 years 1

  • GERtality Score: A 5-point score for severely injured geriatric trauma patients with maximum score of 5 points corresponding to 72.4% mortality rate 1

  • Clinical Frailty Scale (CFS): A 9-point judgment-based tool completed in approximately 24 seconds; scores of 6-7 indicate frailty and independently predict adverse discharge disposition (odds ratio 5.1) and increased complications 1, 2

  • Trauma-Specific Frailty Index (TSFI): A 15-component modified scale validated in geriatric trauma patients; frail patients had 2.5 times higher odds of in-hospital complications 1

What High Scores Mean in Validated Geriatric Tools

High GTOS Score (Trauma Setting)

  • GTOS ≥142 is the optimal cut-off for predicting mortality in elderly trauma patients 1
  • Higher scores indicate increased probability of in-hospital death after injury 1

High GERtality Score (Trauma Setting)

  • Scores of 4-5 points correspond to mortality rates of 47.5-65.1% 1
  • Maximum score of 5 points corresponds to 72.4% mortality 1

High Clinical Frailty Scale (General Geriatrics)

  • CFS scores of 6-7 indicate frailty and are independently associated with adverse discharge destination, increased 30-day mortality, and higher complication rates even with lower injury severity 1, 2
  • All patients who died in prospective geriatric trauma cohorts were classified as frail 1

High CRASH/CARG Scores (Oncology Setting)

  • Higher scores predict increased risk of chemotherapy toxicity (both hematologic and nonhematologic) in older cancer patients 1
  • These tools integrate geriatric assessment domains to guide treatment decisions 1

Clinical Implications of High Geriatric Assessment Scores

When any validated geriatric assessment tool shows high scores indicating vulnerability:

  • Increased mortality risk: Geriatric assessment identifies patients at higher risk of in-hospital death, with functional dependence, malnutrition, and poor social support being foremost predictors 3

  • Higher complication rates: Frail patients have 2.5 times higher odds of in-hospital complications including cardiac, pulmonary, infectious, hematologic, and renal complications 1

  • Functional decline: Depression and impaired instrumental activities of daily living (IADLs) are associated with early functional decline during treatment 1

  • Adverse discharge disposition: High frailty scores predict need for skilled nursing facility placement rather than home discharge 1

  • Treatment toxicity: In oncology, high scores predict inability to complete planned chemotherapy cycles and increased risk of hospitalization 1

Common Pitfall

The critical error is using non-existent assessment tools or confusing acronyms. Always verify you are using validated, evidence-based geriatric assessment instruments with established predictive validity for mortality, morbidity, and quality of life outcomes 1, 2. If someone mentions "RAGE score," clarify which validated tool they actually mean before making clinical decisions.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Frailty Assessment and Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.