From the Research
Eszopiclone is a recommended treatment for insomnia, particularly when comorbid with generalized anxiety disorder, as it has been shown to improve sleep and daytime functioning with minimal risk of tolerance or rebound insomnia 1.
Key Points
- Eszopiclone has been found to be effective in treating insomnia, with a decrease in sleep onset latency and wake time after sleep onset, and an increase in total sleep time 2.
- The combination of eszopiclone and escitalopram has been shown to be well-tolerated and effective in treating insomnia comorbid with generalized anxiety disorder, with improved sleep, daytime functioning, anxiety, and mood 1.
- Insomnia has been linked to an increased risk of hypertension, particularly in those with chronic insomnia and short sleep duration, highlighting the importance of addressing insomnia in the prevention and management of hypertension 3, 4.
- The evidence suggests that eszopiclone is a safe and effective treatment for insomnia, with minimal risk of adverse events, and may be a useful treatment option for patients with insomnia and comorbid conditions such as generalized anxiety disorder or hypertension 2.
Treatment Considerations
- Eszopiclone should be used at the recommended dose of 3 mg nightly, with careful consideration of the potential for adverse events such as unpleasant taste, dry mouth, somnolence, and dizziness 2.
- Patients with insomnia and comorbid conditions such as generalized anxiety disorder or hypertension should be closely monitored for improvements in sleep and daytime functioning, as well as any changes in anxiety or blood pressure 1, 3, 4.
- Further research is needed to fully understand the relationship between insomnia and hypertension, and to determine the effectiveness of insomnia therapy in lowering blood pressure 3, 4.