From the Guidelines
Toujeo does not directly cause increased appetite as a side effect, but it may indirectly lead to increased hunger due to its effect on blood sugar levels. When considering the management of diabetes, as outlined in the 2016 American Diabetes Association standards of medical care in diabetes 1, the focus is on achieving glycemic control through various means, including insulin therapy. Insulin glargine U-300, known by the brand name Toujeo, is a long-acting insulin analog used for basal insulin replacement. The primary concern with insulin therapy is not increased appetite but rather achieving optimal blood glucose levels without causing hypoglycemia. Some key points to consider about insulin therapy and appetite include:
- Insulin lowers blood sugar levels, and if levels drop too low, the body may trigger hunger as a response to encourage eating and raise blood sugar levels.
- Improved blood sugar control with insulin can lead to a return of normal appetite in patients who previously experienced poor appetite due to high blood sugar levels.
- Monitoring blood glucose levels and adjusting insulin dosages or meal timing as needed can help manage hunger and prevent hypoglycemia. Given the information from the 2016 American Diabetes Association standards of medical care in diabetes 1, the focus should be on managing blood sugar levels effectively with insulin therapy, like Toujeo, while being mindful of potential indirect effects on appetite due to changes in blood glucose levels.
From the Research
Toujeo and Appetite
- There is no direct evidence in the provided studies that suggests Toujeo causes increased appetite 2, 3, 4, 5, 6.
- The studies primarily focus on the efficacy, safety, and pharmacokinetics of Toujeo compared to other insulin formulations, such as Lantus, in patients with type 1 and type 2 diabetes.
- Some studies mention changes in body weight, but these are generally reported as either stable or slightly decreased, with no mention of increased appetite as a contributing factor 3, 5.
- The available evidence does not support a link between Toujeo and increased appetite, but it is essential to consult the studies directly for a comprehensive understanding of the topic 2, 3, 4, 5, 6.