Is Rhodiola rosea (Rhodiola) safe to take during pregnancy?

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Last updated: April 17, 2025View editorial policy

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From the Research

Rhodiola is not recommended during pregnancy due to insufficient safety data and potential risks to the developing fetus. Pregnant women should avoid taking rhodiola supplements as there are no adequate studies confirming its safety for the fetus. While rhodiola is sometimes used as an adaptogen for stress relief, fatigue reduction, and mood improvement in the general population, the potential risks to pregnancy outweigh any possible benefits. The active compounds in rhodiola might affect hormone levels and uterine blood flow, which could potentially impact pregnancy.

Some studies have investigated the effects of rhodiola on pregnancy in animal models. For example, a study published in 2014 found that administration of Rhodiola kirilowii extracts to pregnant mice did not change the length of pregnancy, but increased the number of mated females without offspring and caused neonatal deaths in the first 5 days after delivery 1. Another study published in 2017 found that administration of Rhodiola kirilowii extracts during mouse pregnancy and lactation stimulated innate but not adaptive immunity of the offspring 2.

However, the most recent and highest quality study on this topic was published in 2019, which found that long-term supplementation of Rhodiola kirilowii extracts during pregnancy and lactation did not affect mother health status, but had minor effects on the innate immunity of the mothers 3. Despite this, the study recommended caution and further research before using rhodiola as an immunostimulant during pregnancy.

Therefore, if you're pregnant and seeking support for stress, fatigue, or mood issues, it's better to consult with your healthcare provider about pregnancy-safe alternatives. Non-herbal approaches like adequate rest, gentle exercise approved by your doctor, proper nutrition, and professional mental health support are safer options during pregnancy. Always discuss any supplements you're considering with your healthcare provider before taking them during pregnancy. Key considerations for pregnant women include:

  • Avoiding rhodiola supplements due to lack of safety data
  • Consulting healthcare providers for pregnancy-safe alternatives
  • Focusing on non-herbal approaches for stress relief and mood support
  • Prioritizing rest, exercise, nutrition, and mental health support during pregnancy.

References

Research

Long-term supplementation of Rhodiola kirilowii extracts during pregnancy and lactation does not affect mother health status.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2019

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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