Shelf Life of Powdered Retatrutide
I cannot provide specific storage or shelf-life information for powdered retatrutide because no FDA-approved drug label, clinical guidelines, or published research evidence addresses the stability, storage requirements, or shelf life of reconstituted or powdered retatrutide formulations.
Current Regulatory Status
Retatrutide remains an investigational drug that has not received FDA approval, meaning no official prescribing information or storage guidelines exist 1, 2.
- The medication is currently in phase 2 and phase 3 clinical development for obesity and type 2 diabetes treatment 1, 3, 4
- Without FDA approval, there are no established pharmaceutical manufacturing standards or stability data publicly available for clinical use 1
What This Means for Clinical Practice
You should not be handling, storing, or administering powdered retatrutide outside of an approved clinical trial setting where specific storage protocols would be provided by the study sponsor (Eli Lilly and Company) 3, 4.
- Clinical trials of retatrutide have used pre-filled subcutaneous injection formulations, not reconstituted powders 3, 4
- Any powdered formulation obtained outside official channels would be of unknown quality, potency, and safety
- Storage requirements for investigational peptide medications are typically highly specific regarding temperature, humidity, and light exposure, but these have not been published for retatrutide
Common Pitfall to Avoid
Do not attempt to use compounded or non-FDA-approved versions of retatrutide, as there is no validated data on their stability, sterility, or equivalence to the investigational formulations used in clinical trials 3, 4. The safety and efficacy data from published trials cannot be extrapolated to compounded preparations.
If you are participating in a clinical trial involving retatrutide, contact the study coordinator or sponsor for specific storage and handling instructions. If you are seeking this medication for clinical use, it is not yet available outside of research protocols 1.