Is Morton's toe (a condition where the second toe is longer than the first toe) related to Morton's neuroma (thickening of tissue around a nerve in the foot)?

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Morton's Toe and Morton's Neuroma Are Not Related

Morton's toe (a longer second toe) and Morton's neuroma (nerve thickening in the foot) are completely separate conditions with no established relationship. They share only the eponymous name "Morton" but represent distinct anatomical and pathological entities.

Key Distinctions

Morton's Toe

  • An anatomical variant where the second metatarsal bone is longer than the first, making the second toe appear longer 1
  • This is a normal structural variation, not a pathology
  • Named after Dr. Dudley Morton who described this foot structure

Morton's Neuroma

  • A mechanically-induced degenerative neuropathy causing fibrosis (not a true neuroma) of the common digital nerve, most commonly affecting the third web space 2, 3
  • Occurs predominantly in middle-aged women who wear tight, high-heeled shoes 1, 2
  • Results from entrapment or repeated microtrauma to the nerve 1
  • Named after Dr. Thomas Morton who described this nerve condition

Clinical Presentation Differences

Morton's neuroma presents with:

  • Paroxysmal forefoot pain in the web space between toes, typically the third 1, 4
  • Pain triggered by tight footwear, particularly high heels 1
  • Positive Mulder's test on physical examination 1
  • Diagnosis confirmed by ultrasound (90% sensitivity) or MRI (93% sensitivity) 5, 6

Common Pitfall to Avoid

The shared surname "Morton" creates confusion, but these are unrelated conditions. Morton's toe is simply a foot shape variant, while Morton's neuroma is a painful nerve pathology requiring treatment with shoe modifications, corticosteroid injections beside (not into) the neuroma, or surgical excision if conservative measures fail after 4.5 months 7, 8.

References

Research

[Morton's disease].

Brain and nerve = Shinkei kenkyu no shinpo, 2014

Research

Morton neuroma and metatarsalgia.

Current opinion in rheumatology, 2000

Research

Morton's neuroma - Current concepts review.

Journal of clinical orthopaedics and trauma, 2020

Research

Interventions for the treatment of Morton's neuroma.

The Cochrane database of systematic reviews, 2004

Guideline

Diagnostic Approaches for Forefoot Conditions

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Diagnostic Imaging for Morton's Neuroma

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Injection Technique for Morton's Neuroma with Kenalog

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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