Foods Containing EDTA
The evidence provided does not contain any information about EDTA (ethylenediaminetetraacetic acid) in foods or its relevance to patients taking lisdexamfetamine for ADHD.
General Medical Knowledge on EDTA in Foods
EDTA is a synthetic preservative and chelating agent commonly added to processed foods to prevent discoloration, rancidity, and maintain flavor stability. Common food sources include:
- Canned foods - particularly canned vegetables, legumes, and shellfish where EDTA prevents metal-catalyzed oxidation
- Processed sauces and dressings - mayonnaise, salad dressings, and sandwich spreads use EDTA as a preservative
- Carbonated beverages - soft drinks may contain EDTA to preserve flavor and prevent color changes
- Processed seafood products - canned crab, shrimp, and other shellfish commonly contain EDTA
- Margarine and spreads - EDTA prevents oxidative rancidity in fat-containing products
No Known Interaction with Lisdexamfetamine
There is no established clinical interaction between dietary EDTA and lisdexamfetamine (Vyvanse). The mechanism of action of lisdexamfetamine involves enzymatic hydrolysis to release active dextroamphetamine, which enhances dopamine and norepinephrine activity in frontal lobe pathways 1. EDTA functions as a food preservative and does not interfere with this pharmacological process.
Clinical Relevance
If you are asking about EDTA due to concerns about food additives affecting ADHD treatment, focus instead on:
- Timing of meals - taking lisdexamfetamine with high-fat meals may delay absorption
- Acidic foods and beverages - can theoretically affect amphetamine absorption, though clinical significance is minimal with the prodrug formulation
- Consistent medication timing - lisdexamfetamine should be taken in the morning for optimal all-day coverage 2
The question about EDTA appears unrelated to ADHD management with lisdexamfetamine based on current medical evidence.