Is sulfasalazine safe to use in a patient with chronic kidney disease stage 3 (eGFR 30–59 mL/min)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: February 6, 2026View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Related Questions

What are the recommended sulfasalazine dose adjustments for adults with impaired renal function (creatinine clearance 30–50 mL/min, <30 mL/min, and on chronic dialysis)?
Can Sulfasalazine (SSZ) be used to treat inflammatory issues within the urinary tract?
Does Co-amoxyclav (amoxicillin/clavulanic acid) 625 require dosage adjustment in patients with mild renal insufficiency?
Can a patient with impaired renal function (GFR of 34) take methotrexate?
Is Macrobid (nitrofurantoin) safe to prescribe to an elderly female patient with impaired renal function, specifically a Glomerular Filtration Rate (GFR) of 48?
Is taking five standard aspirin tablets (≈400 mg) safe for a patient with chronic kidney disease?
In an older adult with a few‑year history of slowly progressive memory loss, who remains independent in activities of daily living (ADLs) and instrumental activities of daily living (IADLs) and denies falls or wandering, what is the most appropriate next step in evaluation and management?
How should shingles (herpes zoster) be managed in adults, including antiviral therapy, pain control, and vaccination recommendations?
What are the most effective non‑pharmacologic strategies to prevent an older adult with dementia from moving or hiding items, and when is low‑dose antipsychotic medication (e.g., risperidone) appropriate?
Is there any clinical evidence supporting the efficacy of Oberon, the so‑called love potion?
Is Salofalk (mesalamine) safe to use in a patient with chronic kidney disease stage 3?

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.