From the Research
Daflon tablet is generally considered safe for patients with coronary artery disease (CAD) as it primarily treats venous insufficiency and hemorrhoids with minimal effects on the cardiovascular system. The most recent and highest quality study, 1, published in 2021, demonstrated the efficacy of a low-dose diosmin therapy in improving symptoms and quality of life in patients with chronic venous disease, with no treatment-related side effects recorded. This study supports the safety profile of Daflon in patients with CAD.
Key Points to Consider
- Daflon works through anti-inflammatory and venoprotective mechanisms that don't adversely affect cardiac function or blood pressure, which explains its favorable safety profile in cardiac patients.
- The standard dosage of Daflon is 500 mg twice daily, typically taken in the morning and evening with meals.
- CAD patients should still inform their cardiologist before starting Daflon, especially if they take multiple medications, as individual circumstances may vary.
- Daflon doesn't significantly interact with common cardiac medications like antiplatelet drugs, anticoagulants, or antihypertensives, making it suitable for most CAD patients.
Safety and Efficacy
The study 1 showed that low-dose diosmin therapy was safe and effective in relieving symptoms and improving quality of life in subjects with chronic venous disease. Another study, 2, published in 2021, compared the clinical efficacy of diosmin and micronized purified flavonoid fraction for the treatment of chronic venous disorders and found no significant difference between the two forms of diosmin.
Clinical Implications
Based on the available evidence, Daflon can be considered a safe treatment option for CAD patients with venous insufficiency or hemorrhoids, as it has minimal effects on the cardiovascular system and does not significantly interact with common cardiac medications. However, as with any medication, it is essential for CAD patients to consult their cardiologist before starting Daflon, especially if they are taking multiple medications.