Symptomatic Therapy Prescription for Uncomplicated Acute Bronchitis
Do not prescribe antibiotics for uncomplicated acute bronchitis—they provide no meaningful benefit (shortening cough by only ~12 hours) while causing significant adverse effects and promoting resistance. 1
First: Rule Out Pneumonia Before Treating as Simple Bronchitis
Before writing any prescription, verify the patient does NOT have:
- Heart rate >100 beats/min 1, 2
- Respiratory rate >24 breaths/min 1, 2
- Oral temperature >38°C 1, 2
- Abnormal chest findings (rales, egophony, tactile fremitus) 1, 2
If ANY of these are present, obtain chest radiography to rule out pneumonia—this is NOT simple bronchitis. 1, 3
Prescription for Symptomatic Relief
For Bothersome Dry Cough (Especially Nocturnal)
Option 1 (Preferred):
- Dextromethorphan 10-20 mg PO every 4-6 hours as needed
- Maximum 120 mg/24 hours
- Provides modest relief for dry, bothersome cough 1, 3
Option 2 (Alternative):
- Codeine 10-20 mg PO every 4-6 hours as needed
- Maximum 120 mg/24 hours
- Use when dextromethorphan is insufficient 1, 3
For Cough with Wheezing ONLY
Only if wheezing is present on examination:
- Albuterol inhaler 2 puffs (90 mcg/puff) every 4-6 hours as needed
- Maximum 12 puffs/24 hours
- Do NOT prescribe if no wheezing is documented 1, 3, 2
Critical Patient Education (Document This Conversation)
Explain to the patient:
Expected duration: Cough will last 10-14 days and may persist up to 3 weeks even with treatment 1, 3
Why no antibiotics: This is a viral infection (89-95% of cases), and antibiotics:
Green/yellow sputum is NORMAL: Purulent sputum occurs in 89-95% of viral bronchitis and does NOT indicate bacterial infection 1, 5
Non-prescription measures:
When to Return for Reassessment
Instruct the patient to return if:
- Fever persists >3 days (suggests bacterial superinfection or pneumonia) 1
- Cough persists >3 weeks (consider asthma, COPD, pertussis, GERD) 1
- Symptoms worsen rather than gradually improve 1
What NOT to Prescribe
Avoid these medications—they have no proven benefit in acute bronchitis:
- Antibiotics (amoxicillin, azithromycin, doxycycline, etc.) 1, 6
- Expectorants or mucolytics 1, 3
- Antihistamines 1
- Inhaled or oral corticosteroids 1, 3
- NSAIDs at anti-inflammatory doses 1, 3
Exception: Suspected Pertussis
If pertussis is suspected (paroxysmal cough, post-tussive vomiting, inspiratory "whoop," cough >2 weeks):
- Azithromycin 500 mg PO day 1, then 250 mg PO daily × 4 days
- Isolate patient for 5 days from treatment start 1
- This is the ONLY indication for antibiotics in acute bronchitis 1, 6
Common Pitfalls to Avoid
- Do NOT prescribe antibiotics based on sputum color—occurs in 89-95% of viral cases 1, 5
- Do NOT prescribe antibiotics based on cough duration—viral cough normally lasts 10-14 days 1
- Do NOT prescribe bronchodilators without documented wheezing 1, 3
- Do NOT assume early fever (days 1-3) indicates bacterial infection—only fever >3 days warrants reassessment 1
Documentation Template
"Patient counseled that acute bronchitis is viral (89-95% of cases), antibiotics provide no benefit and cause harm. Expected cough duration 10-14 days, up to 3 weeks. Return precautions given for fever >3 days, cough >3 weeks, or worsening symptoms. Patient verbalized understanding and agreement with symptomatic management plan."