For a 270‑lb (≈122 kg) male beginning a weight‑loss program, what is the recommended daily protein intake in grams?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: February 17, 2026View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Recommended Daily Protein Intake for a 270-lb Male Starting Weight Loss

A 270-lb (122 kg) male beginning a weight loss program should consume 146-195 grams of protein per day (1.2-1.6 g/kg body weight), which represents approximately 15-20% of total daily calories. 1, 2

Protein Target Calculation

  • Primary recommendation: 1.2-1.5 g/kg body weight/day for individuals requiring nutritional support during weight loss 1
  • For a 122 kg male, this translates to:
    • Minimum: 146 grams/day (122 kg × 1.2 g/kg)
    • Maximum: 183 grams/day (122 kg × 1.5 g/kg)
  • Optimal range for health outcomes: Evidence supports protein intakes of 1.2-1.6 g/kg/day for achieving optimal health outcomes in adults, which would be 146-195 grams/day for this individual 2

Caloric Context for Weight Loss

  • Men on weight loss programs should target 1500-1800 kcal/day to achieve approximately 0.5 kg/week (1-2 lb/week) weight loss 1
  • At 1500-1800 kcal/day, protein should comprise 15-20% of total calories 1
  • This percentage range (15-20%) aligns with the absolute gram recommendations of 146-195 g/day 1, 3

Rationale for Higher Protein During Weight Loss

Higher protein intake during caloric restriction provides multiple benefits:

  • Preserves lean muscle mass (fat-free mass) while promoting fat loss 4, 5
  • Increases satiety through elevated gut hormones (GLP-1, CCK, PYY) and decreased ghrelin 4
  • Enhances diet-induced thermogenesis, increasing energy expenditure 4
  • Prevents decline in resting energy expenditure by maintaining muscle mass 4
  • Improves body composition outcomes compared to standard protein diets 4, 5

Safety Considerations

  • Long-term protein consumption at 2 g/kg body weight/day (244 grams for this individual) is safe for healthy adults 6
  • The tolerable upper limit is 3.5 g/kg body weight/day for well-adapted individuals 6
  • Critical caveat: If kidney disease is present (eGFR <30 ml/min/1.73m²), protein should be restricted to 0.8 g/kg/day (98 grams) 1
  • Chronic intake >2 g/kg/day may cause digestive, renal, or vascular issues and should be avoided 6

Practical Implementation

Distribute protein evenly across meals:

  • Consuming moderate amounts of high-quality protein at each meal optimally stimulates 24-hour muscle protein synthesis 5
  • For 146-195 grams/day divided across 3 meals: approximately 49-65 grams per meal
  • Prioritize high-quality protein sources from lean meats, fish, poultry, dairy, eggs, and plant-based options 1, 6

Common Pitfalls to Avoid

  • Do not use the standard RDA of 0.8 g/kg/day (98 grams) during active weight loss, as this is insufficient to preserve muscle mass and optimize outcomes 2, 5
  • Avoid excessive protein (>244 grams/day or >2 g/kg/day) without medical supervision, as chronic high intake may cause adverse effects 6
  • Do not neglect resistance training and physical activity, which synergize with higher protein intake to preserve lean mass during weight loss 1, 4

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Protein "requirements" beyond the RDA: implications for optimizing health.

Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2016

Guideline

Protein Goal for Women During Weight Loss

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Clinical Evidence and Mechanisms of High-Protein Diet-Induced Weight Loss.

Journal of obesity & metabolic syndrome, 2020

Research

Protein: A nutrient in focus.

Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2015

Research

Dietary protein intake and human health.

Food & function, 2016

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.