What are the causes of postoperative abdominal distension in a healthy postpartum woman after a lower‑segment cesarean section?

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Postoperative Abdominal Distension After Lower Segment Cesarean Section

Postoperative abdominal distension after LSCS is most commonly caused by postoperative ileus, with key risk factors including opioid analgesia, significant blood loss (>1000 mL), blood transfusion, general anesthesia, and preeclampsia. 1

Primary Mechanism: Postoperative Ileus

The predominant cause of post-LSCS distension is postoperative ileus (POI), which occurs through three main pathways 2:

  • Neurogenic mechanisms: Disruption of sympathetic/parasympathetic pathways to the gastrointestinal tract during surgery 2, 3
  • Inflammatory response: Enteric molecular inflammation with leucocyte recruitment into the intestinal muscularis, impairing neuromuscular function 2
  • Pharmacological factors: Opioid administration for postoperative pain control significantly reduces propulsive GI motility 2, 3

Specific Risk Factors for Post-LSCS Distension

High-Risk Surgical Factors

  • Blood loss >1000 mL: Strongest predictor after multivariable analysis 1
  • Blood transfusion: Independently associated with ileus development 1
  • General anesthesia exposure: Significantly increases risk compared to neuraxial anesthesia 1
  • Hysterectomy at time of cesarean: Associated with prolonged ileus 1
  • Classical hysterotomy or midline vertical incisions: Higher risk than standard transverse approaches 1

Medical Comorbidities

  • Preeclampsia: Identified as independent risk factor for postcesarean ileus 1
  • Magnesium sulfate exposure: More common in cases developing distension 1

Medication-Related Causes

  • Opioid analgesia in labor: Increases risk 4.67-fold for developing acute colonic pseudo-obstruction (ACPO) 4
  • Meperidine for postoperative pain: Specifically implicated in adynamic ileus 5

Acute Colonic Pseudo-Obstruction (Ogilvie Syndrome)

A rare but serious variant occurring in approximately 1 in 800 cesarean sections 4:

  • Clinical presentation: Severe colicky pain, vomiting, and marked abdominal distension occurring immediately or within 2 days postoperatively 5
  • Pathophysiology: Functional ileus of the distal large bowel related to hormonal, autonomic, and metabolic changes from pregnancy and childbirth 4
  • Danger: Insidious onset can lead to delayed diagnosis with risk of bowel ischemia, perforation, and sepsis 4

Other Contributing Factors

Perioperative Fluid Management

  • Fluid overload: Increases risk of cardiovascular work and pulmonary edema, potentially contributing to ileus 6
  • Hypovolemia: Unstable hemodynamic status from significant peripartum hemorrhage predisposes to adynamic ileus 5

Surgical Technique Factors

  • Overt bowel manipulation: Direct handling increases inflammatory response 5
  • Operative duration: Longer, more complex surgeries correlate with higher ileus risk 1

Critical Pitfalls to Avoid

Do not dismiss early distension as "normal postoperative gas" - ACPO can progress rapidly to bowel perforation if unrecognized 4. Obtain CT imaging if distension is severe or accompanied by severe colicky pain and vomiting within 48 hours 5.

Minimize opioid exposure - The ERAS Society strongly recommends multimodal analgesia with intrathecal morphine 50-100 μg, paracetamol, and NSAIDs to reduce systemic opioid requirements that drive ileus 6, 7.

Maintain euvolemia - Both fluid overload and significant blood loss contribute to distension; the ERAS Society provides strong recommendations for perioperative euvolemia 6.

Prevention Strategies Based on Guidelines

  • Neuraxial anesthesia preferred: Regional techniques reduce ileus risk compared to general anesthesia 7, 1
  • Early feeding: Regular diet within 2 hours after cesarean delivery 7
  • Early mobilization: Recommended to facilitate bowel function recovery 7
  • Avoid routine nasogastric decompression: Plays no preventive role and may increase complications 3

References

Research

Risk factors for postoperative ileus after cesarean delivery.

American journal of obstetrics & gynecology MFM, 2022

Research

Mechanisms of postoperative ileus.

Neurogastroenterology and motility, 2004

Research

Pathogenesis and management of postoperative ileus.

Clinics in colon and rectal surgery, 2009

Research

Risk factors for acute colonic pseudo-obstruction after caesarean section: A retrospective case-control study.

The Australian & New Zealand journal of obstetrics & gynaecology, 2023

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Anesthetic and Perioperative Considerations for Cesarean Delivery

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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