What are the causes and treatments of anal pruritus (anal itching)?

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Last updated: February 17, 2025View editorial policy

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Differential Diagnosis for Anal Pruritis

  • Single Most Likely Diagnosis
    • Hemorrhoids: This is often the most common cause of anal pruritis due to the irritation and inflammation of the hemorrhoidal tissue, leading to itching sensations.
  • Other Likely Diagnoses
    • Anal fissure: A tear in the lining of the anus can cause pain, bleeding, and itching due to the exposure of the underlying mucosa and muscle.
    • Fecal incontinence or soiling: Incomplete evacuation of stool or leakage can irritate the anal skin, leading to pruritis.
    • Dermatological conditions (e.g., psoriasis, eczema, lichen sclerosis): These conditions can affect the anal region, causing itching and discomfort.
    • Infections (e.g., candidiasis, bacterial infections): Fungal or bacterial infections in the anal area can cause pruritis, redness, and discharge.
  • Do Not Miss Diagnoses
    • Anal cancer: Although rare, anal cancer can present with persistent pruritis, pain, or bleeding, making it crucial not to miss this diagnosis.
    • Inflammatory bowel disease (e.g., Crohn's disease, ulcerative colitis): These conditions can cause anal symptoms, including pruritis, and have significant implications for patient management and prognosis.
    • STDs (e.g., herpes, syphilis): Certain sexually transmitted diseases can cause anal pruritis, and missing these diagnoses can lead to further complications and transmission to others.
  • Rare Diagnoses
    • Lichen planus: A rare inflammatory condition that can affect the mucous membranes, including the anal region, causing pruritis and discomfort.
    • Leukoplakia: A condition characterized by white patches on the mucous membranes, which can occur in the anal region and cause pruritis.
    • Extramammary Paget's disease: A rare skin condition that can affect the anal region, causing pruritis, redness, and discharge.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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