What is the cause of a red spot on the sclera in pediatric patients?

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Differential Diagnosis for Red Spot on Sclera in Children

  • Single Most Likely Diagnosis
    • Subconjunctival hemorrhage: This is the most common cause of a red spot on the sclera in children, often resulting from minor trauma, coughing, or straining. It appears as a bright red patch and is usually benign and self-limiting.
  • Other Likely Diagnoses
    • Conjunctivitis: Inflammation of the conjunctiva can cause redness and may appear as a spot or more diffuse redness. It can be infectious (viral or bacterial) or allergic.
    • Scleritis: Inflammation of the sclera itself, which can be painful and is less common in children but can be associated with systemic diseases.
    • Episcleritis: An inflammatory condition of the episclera, a thin layer on top of the sclera, which can cause redness and is often benign and self-limiting.
  • Do Not Miss Diagnoses
    • Retinoblastoma with secondary scleral invasion: Although rare, retinoblastoma is a malignant tumor of the retina that can invade the sclera and present with a red spot. Early detection is crucial for treatment and prognosis.
    • Endophthalmitis: A severe infection within the eye that can result from trauma, surgery, or blood-borne infection. It is a medical emergency requiring prompt treatment.
    • Scleral rupture: A serious condition resulting from significant trauma to the eye, which can lead to vision loss if not promptly addressed.
  • Rare Diagnoses
    • Scleral melanoma: A rare tumor of the sclera, more commonly found in adults but can occur in children. It presents as a pigmented lesion rather than a red spot but can have a similar appearance in its early stages.
    • Scleromalacia perforans: A rare, painless, and progressive thinning of the sclera, often associated with systemic autoimmune diseases like rheumatoid arthritis. It is extremely rare in children.
    • Staphyloma: An abnormal protrusion of the uveal tissue (including the sclera) through a weak point, which can be congenital or acquired. It might appear as a red spot or bulge on the sclera.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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