What are the lasting symptoms of postherpetic neuralgia (PHN)?

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From the Research

Lasting Symptoms of Postherpetic Neuralgia (PHN)

The lasting symptoms of PHN include:

  • A constant or intermittent burning, stabbing, or sharp shooting pain with hyperalgesia or allodynia, persisting beyond the healing of herpetic skin lesions 1
  • A steady, aching, boring pain and a paroxysmal lancinating pain, usually exacerbated by contact with the involved skin 2
  • Pain that persists 1 to 3 months following the rash of herpes zoster (HZ) 2
  • Hyperalgesia or allodynia, which can significantly reduce the patient's quality of life 3

Characteristics of PHN

  • PHN affects about 50% of patients over 60 years of age and 15% of all HZ patients 2
  • Elderly patients are at increased risk of PHN 4
  • The pathophysiology of PHN is complex, likely involving both peripheral and central processes 4

Treatment Options for PHN

  • First-line treatments for PHN include tricyclic antidepressants, gabapentin and pregabalin, and the topical lidocaine 5% patch 4
  • Opioids, tramadol, capsaicin cream, and the capsaicin 8% patch are recommended as either second- or third-line therapies in different guidelines 4
  • Interventional pain management options, such as intercostal nerve blocks/neurolysis, stellate ganglion blocks, paravertebral neurolysis, epidural steroid injections, and dorsal root ganglion-radiofrequency ablation, can provide effective and long-lasting pain relief 1
  • Conservative measures, such as hot compresses, can also contribute to symptom relief 3

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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