What are the recommended doses of hydrazine (a toxic substance) in infants?

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Last updated: May 14, 2025View editorial policy

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From the Research

Hydrazine is not recommended for use in infants under any circumstances due to its high toxicity and potential for severe harm or death. The use of hydrazine in infants would pose significant risks to their health, including respiratory irritation, nervous system damage, liver and kidney injury, and potentially fatal outcomes 1.

Key Considerations

  • Hydrazine is a highly toxic chemical compound with no approved medical use in pediatric medicine.
  • Exposure to hydrazine can cause severe health issues, including respiratory problems, nervous system damage, and organ injury.
  • If an infant has been exposed to hydrazine, immediate medical attention is required, focusing on decontamination, supportive care, and symptom management.

Evidence Review

While studies such as those published in 1979 2, 1984 3, 1998 4, and 1975 5 discuss the use of hydrazine sulfate in cancer patients, these findings are not applicable to infants due to the significant differences in physiology, metabolism, and the context of use. The most recent and relevant study regarding the dangers of non-approved substances, including hydrazine, highlights the increased risk of morbidity and mortality associated with their use 1.

Clinical Guidance

Given the potential for severe harm, it is crucial to avoid the use of hydrazine in infants altogether. For any medical concerns or questions about appropriate medication for infants, consultation with a pediatrician is essential to ensure safe and effective treatment, considering the infant's weight, age, and developmental factors.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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