From the Research
Evening primrose oil is not recommended for breast pain treatment due to its lack of efficacy compared to other treatments, as shown in a systematic review and meta-analysis 1. The management of mastalgia involves a variety of treatments, including reassurance, dietary changes, nonsteroidal anti-inflammatory drugs, and hormonal medications 2. Some studies have investigated the use of evening primrose oil for mastalgia treatment, but the results are mixed. A 2021 systematic review and meta-analysis found that evening primrose oil has no difference in reducing breast pain compared to topical NSAIDs, danazol, or vitamin E 1. In contrast, a 2010 randomized pilot study found that evening primrose oil may decrease the severity of cyclical mastalgia, but the results were not significant compared to the placebo group 3. Another study published in 2017 found that flaxseed, but not evening primrose oil or vitamin E, significantly reduced the duration of breast pain 4. A 2004 study discussed the evaluation and management of breast pain, but did not provide specific recommendations for evening primrose oil 5. Given the lack of strong evidence supporting the use of evening primrose oil for breast pain treatment, it is not recommended as a first-line treatment option. Instead, patients with breast pain should be evaluated and managed according to the underlying cause of their symptoms, and treatment options should be individualized based on the patient's specific needs and medical history. Patients should consult with a healthcare provider before starting any new supplements, especially if they are pregnant, breastfeeding, or taking blood-thinning medications.