From the Research
The Mayo score is calculated as the sum of four components: stool frequency, rectal bleeding, endoscopic findings, and physician's global assessment, each scored from 0 to 3, resulting in a total score ranging from 0 to 12. The mathematical equation for the Mayo score is: Mayo score = Stool frequency (0-3) + Rectal bleeding (0-3) + Endoscopic findings (0-3) + Physician's global assessment (0-3) 1. This scoring system is used to assess disease activity in ulcerative colitis, with higher scores indicating more severe disease. Some key points to consider when using the Mayo score include:
- For stool frequency, 0 represents normal stool frequency while 3 indicates ≥5 stools more than normal
- For rectal bleeding, scores range from 0 (no blood) to 3 (mostly blood)
- Endoscopic findings are scored from 0 (normal/inactive disease) to 3 (severe disease with spontaneous bleeding and ulceration)
- The physician's global assessment ranges from 0 (normal) to 3 (severe disease) A total Mayo score of 0-2 typically indicates remission, 3-5 mild disease, 6-10 moderate disease, and 11-12 severe disease, though interpretations may vary slightly between clinical settings 1. It's worth noting that while the provided evidence includes several studies on ulcerative colitis and its treatment, the most relevant information for calculating the Mayo score comes from the study published in 2008 1. Other studies, such as those published in 2020 2, 3, provide information on the treatment of ulcerative colitis, but do not directly address the calculation of the Mayo score. Therefore, the calculation of the Mayo score should be based on the most relevant and up-to-date information available, which in this case is the study published in 2008 1.