From the Guidelines
Omega-3 supplementation is beneficial for certain skin disorders, particularly psoriasis, as it exerts an anti-inflammatory effect via inhibition of inflammatory eicosanoid formation, and can be considered as an additional supplement in patients with chronic plaque psoriasis. The use of omega-3 fatty acid oral supplementation has been shown to be useful as a monotherapy for psoriasis, and may also augment the effects of topical, oral-systemic, and phototherapy for chronic plaque psoriasis 1.
When considering omega-3 supplementation for skin disorders, it is essential to note that the benefits may vary by condition. For inflammatory skin conditions like psoriasis, omega-3 supplements may help reduce inflammation, itching, and scaling when taken consistently for at least 8-12 weeks. Fish oil supplements containing EPA and DHA are most commonly used, and are thought to be more effective than plant-based options like flaxseed oil, which contains ALA and is less efficiently converted in the body.
The benefits of omega-3 supplementation for skin disorders stem from its ability to reduce inflammatory mediators and improve the skin's lipid barrier function. While the evidence is not exhaustive, and more research is needed to fully understand the effects of omega-3 supplementation on various skin conditions, the current evidence suggests that it can be a useful adjunctive treatment for certain skin disorders, particularly psoriasis 1.
Key points to consider when recommending omega-3 supplementation for skin disorders include:
- The potential benefits of omega-3 supplementation for inflammatory skin conditions like psoriasis
- The importance of consistent supplementation for at least 8-12 weeks to see noticeable effects
- The potential side effects of omega-3 supplementation, including fishy aftertaste, gastrointestinal discomfort, and increased bleeding risk, particularly at higher doses or when combined with blood thinners
- The need for omega-3 supplements to complement, not replace, conventional treatments for serious skin conditions.
From the Research
Clinical Benefits of Omega 3 Supplementation in Skin Disorders
- Omega 3 fatty acids have been shown to have potential benefits in the treatment of various skin disorders, including atopic dermatitis and psoriasis 2, 3, 4, 5.
- Studies have demonstrated that omega 3 supplementation can reduce inflammation, improve skin barrier function, and decrease the severity of symptoms in these conditions 2, 3, 4.
- The use of omega 3 fatty acids in combination with other treatments, such as topical corticosteroids, may also be beneficial in reducing the severity of skin disorders 2, 6.
- Omega 3 supplementation has been shown to be safe and well-tolerated, with a low risk of adverse effects 5.
Specific Skin Disorders
- Atopic dermatitis: Omega 3 supplementation has been shown to reduce the severity of symptoms, improve skin barrier function, and decrease the use of topical corticosteroids 2, 3.
- Psoriasis: Omega 3 supplementation has been shown to reduce inflammation, improve skin barrier function, and decrease the severity of symptoms 4, 5.
- Acne: Omega 3 supplementation has been shown to reduce inflammation and improve symptoms 5.
- Skin ulcers: Omega 3 supplementation has been shown to improve wound healing and reduce the severity of symptoms 5.
Mechanisms of Action
- Omega 3 fatty acids have anti-inflammatory effects, which may contribute to their benefits in skin disorders 2, 3, 4.
- Omega 3 fatty acids may also improve skin barrier function, reducing the severity of symptoms in skin disorders 2, 3, 4.
- The use of omega 3 fatty acids in combination with other treatments, such as topical corticosteroids, may also be beneficial in reducing the severity of skin disorders 2, 6.