What is the cause of sudden blindness with new visual hallucinations?

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Last updated: May 17, 2025View editorial policy

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Differential Diagnosis for Blindness plus New Hallucinations

  • Single most likely diagnosis
    • Charles Bonnet Syndrome: This condition is characterized by visual hallucinations in individuals with significant visual impairment or blindness, often due to age-related macular degeneration, cataracts, or other causes of vision loss. The hallucinations can be complex and detailed, and are thought to be related to the brain's attempt to fill in the gaps in visual perception.
  • Other Likely diagnoses
    • Dementia with Lewy Bodies: This neurodegenerative disorder can cause visual hallucinations, cognitive decline, and fluctuations in alertness and attention. Blindness or significant visual impairment can exacerbate the hallucinations.
    • Delirium: A state of acute confusion, delirium can cause hallucinations, disorientation, and altered level of consciousness. Blindness or visual impairment can contribute to the development of delirium, especially in hospitalized or elderly patients.
    • Psychotic Depression: In some cases, individuals with major depressive disorder can experience psychotic symptoms, including hallucinations. Blindness or significant visual impairment can increase the risk of developing psychotic depression.
  • Do Not Miss diagnoses
    • Meningitis or Encephalitis: Infections of the central nervous system can cause hallucinations, blindness, and other neurological symptoms. Prompt diagnosis and treatment are crucial to prevent long-term damage or death.
    • Stroke or Transient Ischemic Attack (TIA): Vascular events can cause sudden blindness and hallucinations, especially if the occipital lobe or other areas involved in vision are affected.
    • Temporal Lobe Seizures: Seizures originating in the temporal lobe can cause hallucinations, blindness, and other neurological symptoms. Untreated seizures can lead to status epilepticus, a life-threatening condition.
  • Rare diagnoses
    • Hallucinogenic Persisting Perception Disorder: A rare condition characterized by persistent hallucinations after the use of hallucinogenic drugs, which can be exacerbated by blindness or visual impairment.
    • Neurosyphilis: A rare infection of the central nervous system caused by syphilis, which can cause hallucinations, blindness, and other neurological symptoms if left untreated.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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