Can ashwagandha help with stress management?

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Last updated: June 6, 2025View editorial policy

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From the Research

Ashwagandha can help with stress management, as evidenced by the most recent and highest quality study, which found that a standardized Ashwagandha root extract alleviates stress, anxiety, and improves quality of life in healthy adults by modulating stress hormones 1.

Key Findings

  • The study published in 2023 found that Ashwagandha root extract (ARE-500 mg) standardized for 2.5% withanolides significantly reduced perceived stress scale (PSS) scores and improved quality of life (QOL) scores in healthy adults with mild to moderate symptoms 1.
  • The effective dose of Ashwagandha root extract was 500mg daily, containing 2.5% withanolides, taken for 60 days 1.
  • Ashwagandha works as an adaptogen, helping the body resist various stressors by modulating the hypothalamic-pituitary-adrenal axis, which controls stress responses.

Important Considerations

  • When purchasing ashwagandha, look for products that specify the withanolide content and consider well-studied extracts.
  • Ashwagandha may interact with certain medications, including thyroid hormones, immunosuppressants, and sedatives, so consult with a healthcare provider before starting, especially if pregnant, breastfeeding, or having autoimmune conditions.
  • While generally considered safe, ashwagandha may cause mild digestive discomfort, and taking it with food can help minimize this side effect.

Summary of Evidence

  • Multiple studies have investigated the effects of ashwagandha on stress and anxiety, with varying results 2, 3, 4, 5.
  • However, the most recent and highest quality study 1 provides the strongest evidence for the effectiveness of ashwagandha in reducing stress and improving quality of life.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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