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Differential Diagnosis for a 54-year-old man with a history of ulcerative colitis and intraabdominal abscess, presenting with painful skin lesions on the neck

  • Single most likely diagnosis
    • Pyoderma gangrenosum: This is a skin condition often associated with inflammatory bowel diseases like ulcerative colitis. The painful skin lesions, especially in the context of a patient with ulcerative colitis, make this a highly plausible diagnosis.
  • Other Likely diagnoses
    • Skin metastasis or seeding from an intraabdominal source: Given the patient's history of an intraabdominal abscess, it's possible that the skin lesions could be a result of bacterial seeding from the abscess.
    • Sweet syndrome (Acute febrile neutrophilic dermatosis): This condition can be associated with inflammatory bowel disease and is characterized by fever, neutrophilia, and tender erythematous skin lesions, which could fit the patient's presentation.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed)
    • Necrotizing fasciitis: Although less common, this is a life-threatening condition that requires immediate attention. The presence of painful skin lesions, especially if accompanied by signs of infection or sepsis, should prompt consideration of this diagnosis.
    • Septic emboli: In the context of an intraabdominal abscess, there's a risk of septic emboli, which could manifest as skin lesions among other symptoms. This would be a critical diagnosis to consider due to its high mortality rate if not promptly treated.
  • Rare diagnoses
    • Erythema nodosum: While this condition can be associated with inflammatory bowel disease, it typically presents with painful nodules on the lower extremities, making it less likely given the neck involvement.
    • Behçet's disease: This rare condition involves inflammation of the blood vessels and can present with a variety of symptoms including skin lesions. However, its rarity and the presence of other more likely explanations make it a less probable diagnosis in this case.

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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