What is the impact of a knowledge gap in dialysis medication administration on patient care in hospitals?

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Last updated: June 13, 2025View editorial policy

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From the Guidelines

Knowledge gaps in dialysis medication administration significantly compromise patient safety and outcomes in hospital settings, leading to medication errors, adverse drug events, and increased healthcare costs, as highlighted in a study published in the American Journal of Kidney Diseases 1. These gaps can result in incorrect dosing, timing, or administration of drugs that should be avoided in dialysis patients, such as antibiotics, anticoagulants, and pain medications. Dialysis patients often require specific dosing schedules coordinated with their dialysis sessions, particularly for medications that are dialyzable, and knowledge gaps can lead to adverse outcomes, including toxicity or treatment failure. Some key points to consider include:

  • Medication reconciliation is a crucial step in identifying and resolving medication-related problems in dialysis patients, as emphasized in a study published in 2020 1.
  • The complexity of medication regimens, altered pharmacokinetics, and frequent care transitions in dialysis patients increase the risk of adverse medication events, as noted in a study published in the same year 1.
  • Implementing a structured medication reconciliation program can help reduce medication discrepancies and improve patient outcomes, as demonstrated in a study that found a significant reduction in hospitalizations and readmissions among dialysis patients who received medication therapy management services 1. Therefore, it is essential to prioritize medication safety in dialysis patients by improving education for healthcare providers, implementing specialized protocols, and fostering collaboration between nephrology, pharmacy, and nursing teams, as recommended in a study published in the American Journal of Kidney Diseases 1. This can be achieved by:
  • Providing regular training and updates on dialysis-specific medication management for healthcare providers
  • Implementing clinical decision support systems to help identify potential medication errors
  • Encouraging collaboration between healthcare teams to ensure accurate medication reconciliation and review
  • Utilizing resources and step-by-step guides to facilitate healthcare providers' efforts to meet the CMS ESRD QIP requirements for medication reconciliation.

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From the Research

Impact of Knowledge Gap on Patient Care

The knowledge gap in dialysis medication administration can have significant effects on overall patient care in hospitals. Some of the key points to consider include:

  • Inadequate knowledge of dialysis medication administration can lead to errors in medication dosing, which can result in adverse patient outcomes 2.
  • A study on educational interventions for patients with chronic kidney disease (CKD) found that well-designed, interactive, and frequent educational interventions can improve patient knowledge, self-management, and outcomes 3.
  • The management of mineral and bone disorders in patients with CKD is critical, and newer compounds such as calcimimetics, phosphate binders, and vitamin D receptor activators can facilitate and improve patient care 4, 5, 6.
  • However, the use of these compounds can be complex, and healthcare providers need to have adequate knowledge and skills to administer them effectively.

Factors Contributing to Knowledge Gap

Several factors can contribute to the knowledge gap in dialysis medication administration, including:

  • Lack of education and training for healthcare providers on dialysis medication administration 2.
  • Limited availability of resources and support for healthcare providers to stay up-to-date with the latest developments in dialysis medication administration 5.
  • Complexity of dialysis medication regimens, which can make it difficult for healthcare providers to keep track of patient medications and dosing schedules 4, 6.

Strategies to Address Knowledge Gap

To address the knowledge gap in dialysis medication administration, several strategies can be employed, including:

  • Providing education and training for healthcare providers on dialysis medication administration 3, 2.
  • Implementing protocols and guidelines for dialysis medication administration to ensure consistency and accuracy 5, 6.
  • Using technology, such as electronic health records and medication management systems, to support healthcare providers in administering dialysis medications 4.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Educational Interventions for Patients With CKD: A Systematic Review.

American journal of kidney diseases : the official journal of the National Kidney Foundation, 2016

Research

State-of-the-Art Management of Hyperphosphatemia in Patients With CKD: An NKF-KDOQI Controversies Perspective.

American journal of kidney diseases : the official journal of the National Kidney Foundation, 2021

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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