What is the treatment for blood-filled pimples?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: June 16, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

Blood-filled pimples can be effectively treated with topical benzoyl peroxide, topical retinoids, or oral doxycycline, as recommended by the most recent guidelines 1. The treatment approach should prioritize reducing inflammation, preventing scarring, and minimizing the risk of infection. Some key considerations for treatment include:

  • Applying a warm compress to the affected area for 10-15 minutes, 2-3 times daily to reduce inflammation and promote healing
  • Using over-the-counter treatments containing benzoyl peroxide (2.5-5%) or salicylic acid (0.5-2%) to dry out the pimple; apply these once or twice daily as directed on the packaging
  • Considering prescription medications like topical retinoids (such as tretinoin 0.025-0.1%) or oral antibiotics (like doxycycline 100mg twice daily for 7-10 days) for persistent or severe cases
  • Avoiding squeezing or popping the pimples to prevent scarring and infection
  • Keeping the area clean by washing with a gentle cleanser twice daily
  • Consulting a dermatologist if the pimples are recurring, painful, or accompanied by other symptoms, as they might indicate a more serious condition like acne vulgaris or a blood clotting disorder that requires specialized treatment 1. It's essential to follow the guidelines of care for the management of acne vulgaris, which recommend limiting the use of systemic antibiotics when possible to reduce the development of antibiotic resistance and other antibiotic-associated complications 1.

From the FDA Drug Label

INDICATIONS AND USAGE Clindamycin Phosphate Topical Solution, Clindamycin Phosphate Gel, and Clindamycin Phosphate Lotion are indicated in the treatment of acne vulgaris. The treatment for blood-filled pimples, which can be a form of acne vulgaris, may include the use of topical antibiotics such as clindamycin phosphate topical solution, gel, or lotion, as indicated in the drug label 2.

  • Key points:
    • Apply the medication as directed by the physician
    • Follow the dosage and administration instructions carefully
    • Be aware of potential side effects, such as diarrhea, bloody diarrhea, and pseudomembranous colitis However, it is essential to consult a physician for proper evaluation and treatment, as the specific treatment may vary depending on the individual case and the severity of the condition.

From the Research

Treatment for Blood-Filled Pimples

There are various treatments available for acne, including blood-filled pimples. The treatment approach may vary depending on the severity and type of acne.

  • Topical retinoids and antibiotics are commonly used in combination for the management of acne, as they target multiple pathogenic factors associated with acne 3.
  • For acne scarring, laser treatment is considered the most effective option, but it's essential to consider the skin type and potential risks of adverse effects, such as postinflammatory hyperpigmentation 4.
  • Topical management of acne scars is also an option, with agents like retinoids, tacrolimus, and glycolic acid being explored, although more research is needed to support their widespread use 5.
  • Topical antimicrobial agents, such as benzoyl peroxide and clindamycin, can be used to reduce bacterial counts and inflammatory lesions in mild to moderate acne 6.
  • In the case of acne-induced pathological scars, treatments targeting inflammatory responses and fibrosis are being explored, including the use of regulatory T cells to suppress fibrosis production 7.

Considerations for Treatment

When considering treatment for blood-filled pimples, it's crucial to:

  • Consult a dermatologist to determine the best course of treatment based on individual needs and skin type.
  • Be aware of potential risks and adverse effects associated with different treatments.
  • Combine treatments to target multiple aspects of acne and scarring.
  • Consider maintenance therapies after procedures to ensure optimal results.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Topical retinoid and antibiotic combination therapy for acne management.

Journal of drugs in dermatology : JDD, 2004

Research

Laser treatment of acne scarring in skin of colour.

Clinical and experimental dermatology, 2023

Research

Topical management of acne scars: The uncharted terrain.

Journal of cosmetic dermatology, 2023

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.