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From the Research
Causes of Eyelid Popping
The causes of eyelid popping, also known as floppy eyelid syndrome, are numerous and can be associated with significant ocular irritation. Some of the possible causes include:
- Eyelid hyperlaxity with reactive palpebral conjunctivitis 1
- Decreased amount of elastin within the tarsus, leading to laxity of the lid 2
- Systemic associations such as keratoconus and obstructive sleep apnea 1, 3
- Ocular associations such as papillary keratoconjunctivitis 2
Associated Conditions
Eyelid popping can be associated with various conditions, including:
- Lower lid malposition, which encompasses a spectrum of lower eyelid conditions ranging from lower lid retraction to frank ectropion and entropion 4
- Obstructive sleep apnea, which can cause eyelid laxity and popping 1, 3
- Keratoconus, a systemic disease that can be associated with floppy eyelid syndrome 1, 3
Pathogenesis
The underlying pathogenesis of eyelid popping remains elusive, although progress has been made in the identification of extracellular matrix changes in the tarsal plate 3. Further research is needed to fully understand the causes and mechanisms of eyelid popping.