From the Research
NMN supplementation is primarily taken to boost NAD+ levels in the body, which decline with age, and its potential benefits include improving metabolic health, promoting longevity, and supporting cellular energy production. The scientific reasoning behind NMN supplementation is that it serves as a precursor to NAD+, a coenzyme essential for hundreds of metabolic processes including DNA repair, energy metabolism, and cellular signaling 1. As we age, NAD+ levels naturally decrease, which may contribute to various aspects of aging and age-related diseases.
Key Points to Consider
- NMN is believed to support cellular energy production, promote longevity, and potentially improve metabolic health 2
- The decline in NAD+ levels with aging impairs tissue function, which has been associated with several age-related diseases 3
- Human clinical evidence remains limited, but studies have shown that NMN supplementation can increase NAD+ levels in healthy subjects 4
- NMN supplementation has been shown to be safe and well-tolerated in healthy adult men and women in doses up to 1250mg daily for up to 4 weeks 5
Important Considerations
- Those considering NMN should be aware that it's relatively expensive and lacks long-term safety data in humans
- It is essential to consult with a healthcare provider before starting NMN supplementation, especially if taking medications or having existing health conditions
- More research is needed to fully understand the effects of NMN supplementation on human health and to determine the optimal dosage and duration of treatment 1, 3