What is the proper procedure for interpreting an electrocardiogram (ECG)?

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Proper Procedure for Interpreting an Electrocardiogram (ECG)

A systematic approach to ECG interpretation must follow a structured algorithm that includes rate, intervals, rhythm, and ischemia/infarction assessment (RIRI approach), with mandatory physician overreading of all computer-generated interpretations to ensure accurate diagnosis and appropriate patient management. 1, 2

Technical Considerations Before Interpretation

  • Verify proper lead placement and recording quality with standard calibration (10 mm/mV and 25 mm/s)
  • Ensure adequate bandwidth (≥150 Hz for adults/adolescents, ≥250 Hz for children)
  • Compare with previous ECGs when available
  • Check for technical artifacts that may affect interpretation

Step-by-Step ECG Interpretation Algorithm

1. Rate Assessment

  • Calculate heart rate (normal: 60-100 beats/min)
  • Identify bradycardia (<60 beats/min) or tachycardia (>100 beats/min)

2. Interval Measurements

  • PR interval (normal: 120-200 ms)
  • QRS duration (normal: <120 ms)
  • QT interval (corrected for heart rate using QTc)
    • Normal QTc: <450 ms in men, <460 ms in women 1

3. Rhythm Analysis

  • Identify P waves (normal duration <120 ms, amplitude <2.5 mm)
  • Assess P-QRS relationship for AV conduction
  • Classify as sinus rhythm or identify specific arrhythmias

4. Ischemia/Infarction Evaluation

  • Examine for ST segment deviations:
    • ST elevation ≥0.1 mV (1 mm) in two contiguous leads suggests myocardial injury
    • Different thresholds for ST elevation in V2-V3 by gender and age:
      • ≥0.2 mV (2 mm) in men ≥40 years
      • ≥0.25 mV (2.5 mm) in men <40 years
      • ≥0.15 mV (1.5 mm) in women 1
  • Assess for pathological Q waves (>40 ms or >25% of R wave amplitude)
  • Evaluate T wave morphology (inversions, hyperacute changes)

5. Chamber Abnormalities Assessment

  • Left ventricular hypertrophy (using Sokolow-Lyon or Cornell criteria)
  • Right ventricular hypertrophy (R in V1 >7 mm or R/S ratio in V1 >1) 1

6. Conduction Abnormalities Evaluation

  • Bundle branch blocks
  • Fascicular blocks
  • AV blocks

Critical Considerations

Competency Requirements

  • Physicians should interpret at least 500-800 ECGs under supervision to develop competency
  • Maintain proficiency by interpreting at least 100 ECGs yearly
  • Formal training in ECG interpretation during residency or fellowship is essential 1

Computer Algorithm Limitations

  • Error rates up to 40.7% for acute myocardial infarction
  • Only 0-94% of disorders classified correctly
  • All computer-based reports require physician overreading 3, 1

Common Pitfalls to Avoid

  1. Misdiagnosis of mimicking conditions: Both cardiac and non-cardiac conditions can mimic acute myocardial infarction on ECG, including pericarditis, stress-induced cardiomyopathy, and post-ictal changes 4
  2. Relying solely on computer interpretation: Computer algorithms have significant limitations and should never replace physician interpretation 3, 1
  3. Failure to compare with previous ECGs: Serial comparison of ECGs should be done by trained observers regardless of whether the ECG program provides a serial comparison 3
  4. Isolated interpretation without clinical context: ECG findings must be integrated with clinical data and patient-specific context 1

Special Considerations

  • Major interpretation errors are common (4-33%) even among trained physicians 1
  • Time-dependent conditions require rapid and accurate ECG interpretation
  • Periodic objective assessment of interpretation skills in clinical context is more important than completing a minimum number of interpretations 1

By following this systematic approach to ECG interpretation, clinicians can minimize errors, improve diagnostic accuracy, and ensure appropriate patient management based on accurate ECG interpretation.

References

Guideline

Electrocardiogram Interpretation

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

A novel systematic approach to ECG interpretation.

Dynamics (Pembroke, Ont.), 2005

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Clinical Significance of Conditions Presenting with ECG Changes Mimicking Acute Myocardial Infarction.

The International journal of angiology : official publication of the International College of Angiology, Inc, 2013

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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