Treatment for Tympanic Membrane Perforation
Most tympanic membrane perforations heal spontaneously with conservative management, requiring only watchful waiting, keeping the ear dry, and appropriate follow-up. 1, 2
Initial Management
Assessment and Classification
- Determine cause of perforation:
- Trauma (blunt or penetrating)
- Acute otitis media
- Chronic middle ear infection
- Evaluate size and location of perforation
- Check for signs requiring urgent ENT referral:
- Continuous pain
- Vertigo
- Facial paralysis
- Significant hearing loss (>30 dB)
Conservative Management (First-Line)
Keep the ear dry 2
- Avoid swimming until cleared by physician
- Use earplugs or petroleum jelly-coated cotton when showering 3
- Avoid activities that create pressure changes
Watchful waiting 1
- 95% of traumatic perforations heal spontaneously with this approach
- All children demonstrate complete spontaneous recovery 4
Pain management 3
- Mild to moderate pain: Acetaminophen or NSAIDs
- Severe pain: May require combination analgesics with opioids
Infection Management
For perforations caused by acute otitis media:
For infected perforations:
- Topical non-ototoxic fluoroquinolone drops (ofloxacin 0.3%) are more effective than systemic antibiotics
- Recommended dosage: Ten drops (0.5 mL) twice daily for 14 days 3
For fungal infections:
Follow-Up and Monitoring
Expected Healing Timeline
- Middle ear effusion resolution rates:
- 2 weeks: 30-40%
- 1 month: 60-70%
- 3 months: 75-90% 3
When to Refer to ENT
- Perforation failing to heal after 3 months
- Significant hearing loss (>30 dB conductive loss)
- Persistent vertigo
- Facial nerve weakness
- Suspected cholesteatoma formation 3, 5
- Blast injuries (higher risk of secondary cholesteatoma) 1
Surgical Management (Second-Line)
Indications for Surgical Intervention
- Chronic perforation that doesn't heal spontaneously
- Perforations due to chronic middle ear infection or cholesteatoma 2
- Significant hearing loss due to the perforation
Surgical Options
- Tympanoplasty for persistent perforations 4
- Success rates are high, with most patients achieving complete closure 4
Special Considerations
Population-Specific Management
- Children: Take longer to clear effusions, especially those under 2 years 3
- Diabetic patients: Require closer monitoring due to higher risk of malignant otitis externa 3
- Immunocompromised patients: More susceptible to otomycosis and necrotizing otitis externa 3
- Elderly patients: Should be vigilant for necrotizing otitis externa 3
Important Precautions
- Avoid irrigation of the ear canal 5
- Avoid pneumatic otoscopy 5
- Carefully suction blood, purulent secretions, and debris from the ear canal 5
Potential Complications
- Conductive hearing loss (1.8-11% of cases) 3
- Persistent tympanic membrane perforation (1-4.2% of cases) 3
- Ossicular chain disruption (3.6% of cases) 3
- Recurrent middle ear infections 2
The high rate of spontaneous healing (95% for traumatic perforations) supports a conservative approach as first-line management for most tympanic membrane perforations 1. Surgical intervention should be reserved for perforations that fail to heal after 3 months or those associated with chronic middle ear disease.