What size tracheal tube is used for newborn intubation?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: October 4, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Endotracheal Tube Size for Newborn Intubation

For newborn intubation, a 3.0 mm internal diameter (ID) cuffed tracheal tube should be used for infants weighing ≥3.5 kg and less than 1 year of age. 1

Recommended Tracheal Tube Sizes for Newborns

  • For newborns weighing ≥3.5 kg, use a 3.0 mm ID cuffed tracheal tube 1
  • If using an uncuffed tube for newborns, a 3.5 mm ID tube is appropriate 2
  • Have tubes 0.5 mm smaller and 0.5 mm larger than the estimated size available during intubation 2
  • Recent evidence suggests that for smaller newborns (1000-1199g), a 2.5 mm tube may be associated with fewer adverse events than the standard 3.0 mm recommendation 3

Tube Selection Considerations

  • Both cuffed and uncuffed tracheal tubes are acceptable for newborn intubation 1, 2
  • Cuffed tubes may be preferable in certain circumstances such as poor lung compliance, high airway resistance, or large glottic air leak 1, 2
  • If using cuffed tubes, monitor cuff pressure and keep it below 25 cm H2O to prevent airway damage 1, 2
  • The 3.0 mm tube size recommendation is based on multiple prospective studies including LOE 2 prospective randomized multicenter studies 1

Proper Tube Placement

  • Depth of insertion (cm at lip) = weight in kg + 6 cm 2
  • Alternatively, depth can be estimated as 3 times the internal diameter of the tube 2, 4
  • The tube should be inserted to approximately 50-55% of tracheal length 4
  • Verify proper tube placement using multiple methods including:
    • Bilateral chest movement 2
    • Equal breath sounds over both lung fields 2
    • Absence of gastric insufflation sounds 2
    • End-tidal CO2 detection 2

Troubleshooting

  • If the tracheal tube meets resistance during insertion, use a tube with an ID 0.5 mm smaller 1, 2
  • If there is no leak around the tube with the cuff deflated, reintubation with a tube ID 0.5 mm smaller may be beneficial when the patient is stable 1
  • Be aware that smaller tubes (2.5 mm) have significantly higher resistance, which may increase work of breathing in spontaneously breathing infants 5

Clinical Considerations

  • A very small ETT increases the risk of inadequate ventilation, air leakage, and aspiration, while a very large ETT may cause airway damage, post-intubation croup, and subglottic stenosis 6
  • Recent research suggests that for some weight categories, tubes 0.5 mm smaller than standard recommendations may be associated with fewer adverse events during intubation, including less severe oxygen desaturation 3
  • Remember the "DOPE" mnemonic if a patient's condition deteriorates after intubation: Displacement, Obstruction, Pneumothorax, Equipment failure 2

The evidence strongly supports using a 3.0 mm ID cuffed tracheal tube for newborn intubation in infants weighing ≥3.5 kg, based on multiple high-quality studies and international guidelines. This recommendation balances the need for adequate ventilation while minimizing the risk of airway trauma.

References

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.