How to treat peeling skin caused by Hand, Foot, and Mouth Disease (HFMD)?

Treatment of Peeling Skin from Hand, Foot, and Mouth Disease

The most effective treatment for peeling skin caused by Hand, Foot, and Mouth Disease (HFMD) is regular application of moisturizers to create an occlusive barrier, combined with gentle skin care practices. 1

Understanding HFMD-Related Skin Peeling

• HFMD is a viral infection commonly caused by Coxsackieviruses that typically resolves within 7-10 days, with skin lesions healing and subsequently peeling 2
• The peeling phase often occurs during recovery as the skin repairs itself, particularly on palms and soles 3
• Peeling skin is a normal part of the healing process and usually occurs after the infectious phase has passed 2

Primary Treatment Approach

Moisturization Strategy

• Apply moisturizers regularly to affected areas to maintain skin hydration and promote healing 1
• Use water-based moisturizers rather than greasy or oil-based products which may worsen irritation 1
• Apply moisturizer immediately after washing hands or bathing while skin is still damp to lock in moisture 1
• For severe cases, consider the "soak and smear" technique:
  • Soak affected areas in plain water for 20 minutes 1
  • Immediately apply moisturizer to damp skin 1
  • Repeat nightly for up to 2 weeks until healing is complete 1

Gentle Skin Care Practices

• Use gentle pH5 neutral soaps and tepid water when washing affected areas 1
• Pat skin dry with clean, soft towels rather than rubbing 1
• Wear loose-fitting, fine cotton clothing to minimize friction and irritation 1
• Avoid hot water which can further dry and irritate peeling skin 1

Management of Discomfort

• For pain or discomfort, use acetaminophen or ibuprofen as needed 2
• Avoid topical lidocaine preparations as they are not recommended for HFMD 2
• For severe irritation that doesn't respond to moisturizers, consider application of a low-potency topical steroid under medical supervision 1

What to Avoid

• Avoid manipulating or picking at peeling skin as this increases risk of infection 1
• Do not use greasy creams which may have occlusive properties that worsen irritation 1
• Avoid harsh soaps, detergents, and skin irritants that can delay healing 1
• Avoid hot blow-drying of affected areas 1
• Do not use topical antibiotics (e.g., neomycin, bacitracin) unless specifically prescribed for secondary infection 1

Prevention of Secondary Complications

• Keep affected areas clean and dry to prevent secondary bacterial infection 1
• If signs of infection develop (increased redness, warmth, swelling, pus), consult a healthcare provider 1
• For persistent or worsening symptoms beyond 2 weeks, seek medical evaluation 1

Special Considerations for Nighttime Care

• Apply a thicker layer of moisturizer at night for enhanced hydration 1
• For severe cases, consider wearing cotton gloves after applying moisturizer to create an occlusive barrier overnight 1
• This nighttime occlusion can significantly accelerate healing of peeling skin 1