What is the treatment for bleeding through a Nasogastric (NG) tube?

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Last updated: October 6, 2025View editorial policy

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Management of Bleeding Through a Nasogastric (NG) Tube

The treatment for bleeding through a nasogastric tube requires immediate assessment of the bleeding source and implementation of appropriate hemostatic measures, with endoscopic evaluation being the primary intervention for most cases.

Initial Assessment and Management

  • Assess hemodynamic stability and provide resuscitation if needed with intravenous fluids and blood products, maintaining hemoglobin at 70-80 g/L 1
  • Consider proton pump inhibitor (PPI) administration after initial resuscitation to reduce risk of ongoing bleeding 1
  • Perform urgent endoscopic evaluation within 24 hours, with earlier endoscopy for high-risk patients with hemodynamic instability 1, 2
  • Do not remove the NG tube until the source of bleeding is identified, as it can help monitor ongoing bleeding 3

Diagnostic Approach

  • Bloody NG aspirate requires investigation to determine the source of bleeding:
    • Bright red blood or "coffee grounds" appearance in NG aspirate strongly correlates with upper GI bleeding source (95% diagnostic yield on endoscopy) 3
    • Clear aspirate suggests lower GI source (56% diagnostic yield on lower endoscopy) 3
  • Consider upper endoscopy as the first diagnostic step when blood is present in NG aspirate 2, 3

Management Based on Bleeding Source

Gastric Varices Bleeding

  • For bleeding gastric varices identified on endoscopy:
    • Cyanoacrylate injection is the treatment of choice 2
    • Consider balloon-occluded retrograde transvenous obliteration (BRTO) if a gastrorenal shunt is present 2
    • Transjugular intrahepatic portosystemic shunt (TIPS) may be used when there is significant inflow from the coronary vein 2

Non-variceal Upper GI Bleeding

  • For ulcers or erosions:
    • Apply endoscopic therapy (injection, thermal probes, or clips) for lesions with active bleeding or non-bleeding visible vessels 1, 2
    • Continue high-dose PPI therapy after endoscopic treatment 1
    • For refractory bleeding, consider interventional radiology (angiographic embolization) or surgery 1

Radiation-induced Bleeding

  • Consider external beam radiation therapy for chronic blood loss due to gastric cancer or radiation-induced damage 2
  • Formalin application may be effective for radiation-damaged tissues 2

Post-treatment Management

  • After successful hemostasis:
    • Monitor for rebleeding through the NG tube 2
    • For patients with high-risk lesions (Forrest I-IIb ulcers or variceal bleeding), wait at least 48 hours after endoscopic therapy before resuming oral or enteral feeding 4
    • For low-risk lesions (Forrest IIc and III ulcers, gastritis, Mallory-Weiss tears, esophagitis, or angiodysplasia), feeding can be resumed as soon as tolerated 4

Special Considerations

  • NG tube insertion should be avoided for three days after acute variceal bleeding 2
  • Only fine bore tubes should be used in patients with recent variceal bleeding to minimize trauma 2
  • Long-term NG tubes should be changed every 4-6 weeks, alternating nostrils to prevent complications 2
  • Consider gastrostomy or jejunostomy feeding if enteral nutrition is required for more than 4-6 weeks 2

Complications to Monitor

  • NG tube-related complications include nasopharyngeal discomfort, nasal erosions, sinusitis, and rarely esophageal damage 2
  • Monitor for tube displacement, which occurs in approximately 25% of cases 2
  • Watch for signs of rebleeding, which may require repeat endoscopic therapy 1

Prevention of Recurrent Bleeding

  • In ICU patients, enteral nutrition may serve as stress ulcer prophylaxis 4
  • For patients requiring antithrombotic agents, early reintroduction appears to improve outcomes after bleeding is controlled 1
  • Consider timing of reintroduction of antithrombotic therapy in consultation with the service that initiated the therapy 2

References

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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