Is naproxen (nonsteroidal anti-inflammatory drug) safe for a 23-year-old with normal blood pressure and a shoulder strain for 3 days?

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Naproxen Safety for a 23-Year-Old with Shoulder Strain

Naproxen is safe and appropriate for short-term use (3 days) in a healthy 23-year-old with normal blood pressure (123/89) and a shoulder strain. 1

Safety Profile for Young Adults with Normal Blood Pressure

  • Naproxen is generally well-tolerated for short-term use in young, healthy individuals without pre-existing cardiovascular, renal, or gastrointestinal conditions 2, 1
  • The 3-day duration minimizes risk of adverse effects, as most NSAID complications occur with prolonged use or in high-risk populations 2
  • A blood pressure of 123/89 is within normal range and does not indicate hypertension that would contraindicate NSAID use 3

Efficacy for Shoulder Pain

  • Naproxen has demonstrated effectiveness in treating acute shoulder pain and musculoskeletal conditions like shoulder strain 4, 5
  • Studies show naproxen significantly reduces pain and improves subjective impression of shoulder restriction in patients with shoulder conditions 4

Risk Assessment for This Specific Patient

  • Young age (23 years) is protective against most NSAID-related complications, as risk increases linearly at approximately 4% per year of advancing age 2
  • Short duration therapy (3 days) significantly reduces risk compared to chronic use 2
  • Normal blood pressure indicates low cardiovascular risk 3, 6
  • Absence of other risk factors (no mention of gastrointestinal, renal, or cardiovascular disease) places this patient in a low-risk category 2, 3

Precautions to Consider

  • Even short-term NSAID use carries a small risk of gastrointestinal effects, though these are significantly less common in young, healthy individuals 3
  • Patient should be advised to take naproxen with food to minimize potential gastrointestinal irritation 2
  • If pain persists beyond 3 days, reevaluation is recommended rather than continuing naproxen long-term 2
  • Patient should be advised to avoid alcohol while taking naproxen to reduce risk of gastrointestinal irritation 2

Dosing Recommendations

  • Standard over-the-counter dosing (220-440 mg twice daily) is appropriate for this indication 1
  • The lowest effective dose should be used for the shortest duration needed to control symptoms 3
  • Total daily dose should not exceed 1000 mg for over-the-counter use 1

In conclusion, the 3-day course of naproxen for a shoulder strain in this young adult with normal blood pressure presents minimal risk and is an appropriate first-line treatment option.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Naproxen and indomethacin in periarthritis of the shoulder.

Rheumatology and rehabilitation, 1982

Research

Celecoxib is as efficacious as naproxen in the management of acute shoulder pain.

The Journal of international medical research, 2003

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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