Is Oral PEG available in my location?

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Last updated: November 23, 2025View editorial policy

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Oral PEG Availability

Oral polyethylene glycol (PEG) is widely available in the United States and most developed countries both as over-the-counter (OTC) and prescription formulations. However, I cannot confirm availability in your specific location without knowing where you are located.

Available Formulations

Over-the-Counter Products

  • PEG-3350 powder is available OTC as an 8.3-oz bottle (238 g) marketed for constipation 1, 2
  • This formulation is FDA-approved for occasional constipation and can be purchased without a prescription 1, 2
  • The standard OTC dose is 17 grams dissolved in 4-8 ounces of beverage, used once daily for up to 7 days 2

Prescription Formulations

Multiple FDA-approved prescription PEG-based bowel preparations are available for colonoscopy, including 1:

  • 4-L PEG-ELS formulations: Colyte, Gavilyte, Golytely, and Nulytely (sulfate-free)
  • 2-L PEG-ELS formulations: MoviPrep (with ascorbate and sodium sulfate)
  • 1-L PEG-ELS formulations: Ultra-low-volume preparations with ascorbate 1

Clinical Context

For Constipation Management

  • PEG-3350 is effective for chronic idiopathic constipation, with moderate-quality evidence supporting its use 1
  • It can be used for up to 6 months safely in patients with chronic constipation 1
  • The medication is relatively inexpensive and widely accessible 1

For Bowel Preparation

  • Split-dose regimens of 4-L PEG-ELS provide high-quality bowel cleansing with strong recommendation and high-quality evidence 1
  • Lower-volume formulations (2-L and 1-L) demonstrate comparable efficacy with better patient tolerability and adherence 1

Important Considerations

Contraindications and warnings from FDA labeling include 2:

  • Do not use if allergic to polyethylene glycol
  • Do not use if you have kidney disease without physician supervision
  • Avoid in patients with nausea, vomiting, abdominal pain, or sudden bowel habit changes
  • Not recommended for irritable bowel syndrome without medical consultation

To determine availability in your specific location, you should:

  • Check with local pharmacies for OTC PEG-3350 products
  • Consult with a local physician who can prescribe prescription PEG formulations if needed
  • Verify regulatory approval status in your country, as availability varies by region

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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