Oral PEG Availability
Oral polyethylene glycol (PEG) is widely available in the United States and most developed countries both as over-the-counter (OTC) and prescription formulations. However, I cannot confirm availability in your specific location without knowing where you are located.
Available Formulations
Over-the-Counter Products
- PEG-3350 powder is available OTC as an 8.3-oz bottle (238 g) marketed for constipation 1, 2
- This formulation is FDA-approved for occasional constipation and can be purchased without a prescription 1, 2
- The standard OTC dose is 17 grams dissolved in 4-8 ounces of beverage, used once daily for up to 7 days 2
Prescription Formulations
Multiple FDA-approved prescription PEG-based bowel preparations are available for colonoscopy, including 1:
- 4-L PEG-ELS formulations: Colyte, Gavilyte, Golytely, and Nulytely (sulfate-free)
- 2-L PEG-ELS formulations: MoviPrep (with ascorbate and sodium sulfate)
- 1-L PEG-ELS formulations: Ultra-low-volume preparations with ascorbate 1
Clinical Context
For Constipation Management
- PEG-3350 is effective for chronic idiopathic constipation, with moderate-quality evidence supporting its use 1
- It can be used for up to 6 months safely in patients with chronic constipation 1
- The medication is relatively inexpensive and widely accessible 1
For Bowel Preparation
- Split-dose regimens of 4-L PEG-ELS provide high-quality bowel cleansing with strong recommendation and high-quality evidence 1
- Lower-volume formulations (2-L and 1-L) demonstrate comparable efficacy with better patient tolerability and adherence 1
Important Considerations
Contraindications and warnings from FDA labeling include 2:
- Do not use if allergic to polyethylene glycol
- Do not use if you have kidney disease without physician supervision
- Avoid in patients with nausea, vomiting, abdominal pain, or sudden bowel habit changes
- Not recommended for irritable bowel syndrome without medical consultation
To determine availability in your specific location, you should:
- Check with local pharmacies for OTC PEG-3350 products
- Consult with a local physician who can prescribe prescription PEG formulations if needed
- Verify regulatory approval status in your country, as availability varies by region