What medications can be continued in a COPD patient undergoing surgery for a right intertrochanteric (IT) fracture who is currently taking livolin (bronchodilator), formonide (corticosteroid), nebzmart, g siladol (pain management), and urispas (urinary issues)?

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Perioperative Medication Management for COPD Patient Undergoing Hip Fracture Surgery

Continue all COPD maintenance medications (livolin/bronchodilator, formonide/corticosteroid, nebzmart) through the morning of surgery, and resume them as soon as possible postoperatively. 1

Medications to Continue

COPD Maintenance Therapy - MUST CONTINUE

  • Long-acting bronchodilators (LABA/LAMA) and inhaled corticosteroids should be continued perioperatively to prevent acute exacerbations and postoperative pulmonary complications 1, 2

  • Formonide (formoterol + corticosteroid combination) should be continued through surgery, as withdrawal increases risk of COPD exacerbation and postoperative respiratory failure 2, 3

  • Livolin (bronchodilator) should be continued, as bronchodilators reduce postoperative pulmonary complications in COPD patients 4, 2

  • Nebzmart (if this is a nebulized bronchodilator) should be continued, though may need to switch to metered-dose inhaler or continue nebulization postoperatively 1

  • Studies show that introducing or continuing COPD treatment perioperatively reduces postoperative pulmonary complications by 91% (OR 0.09,95% CI 0.01-0.81) 2

Pain Management

  • G siladol (analgesic) can be continued but coordinate with anesthesia team regarding timing of last dose before surgery 5

  • Ensure adequate postoperative pain control is planned, as uncontrolled pain impairs respiratory mechanics in COPD patients 4

Urinary Medications

  • Urispas (flavoxate - urinary antispasmodic) can be continued perioperatively as it does not significantly impact surgical risk 5

Critical Perioperative Considerations

High-Risk Population

  • COPD patients have 7.6-fold increased 30-day mortality after surgery (6.1% vs 0.8% in controls, P=0.03) 4

  • Postoperative respiratory failure occurs in 10.4% of COPD patients versus 2.5% in non-COPD patients (P=0.02) 4

  • Upper abdominal or thoracic surgery carries highest risk, but orthopedic surgery still poses significant pulmonary risk 2

Medication Timing on Surgery Day

  • Administer morning doses of all COPD medications on the day of surgery, ideally 2-4 hours before anesthesia 1, 5

  • Do NOT withhold bronchodilators or inhaled corticosteroids - withdrawal potential and disease progression risk outweigh any theoretical anesthetic interactions 5

  • Coordinate with anesthesia regarding G siladol timing to avoid drug interactions 5

Postoperative Management

  • Resume all COPD medications immediately when patient can take oral/inhaled medications, ideally within 4-6 hours postoperatively 1, 3

  • Use nebulized bronchodilators initially if patient cannot use inhalers effectively due to pain or positioning restrictions 1

  • Monitor for exacerbations closely - COPD patients have longer ICU stays (P=0.02) and hospital stays (P=0.04) after surgery 4

Common Pitfalls to Avoid

  • Never discontinue inhaled corticosteroids perioperatively - this dramatically increases exacerbation risk and postoperative complications 1, 2, 3

  • Do not substitute short-acting for long-acting bronchodilators perioperatively - maintain the patient's established regimen 1

  • Avoid oxygen-driven nebulizers if patient develops hypercapnia postoperatively - use compressed air with supplemental oxygen via nasal cannula 1, 6

  • Monitor arterial blood gases if patient shows signs of respiratory distress, as bronchodilators can affect CO2 levels 6

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Management and prevention of exacerbations of COPD.

BMJ (Clinical research ed.), 2014

Guideline

Medications Affecting Carbon Dioxide Levels in COPD Patients

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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