How do I order a separate pen injector for an insulin (or other injectable medication) cartridge?

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Last updated: December 23, 2025View editorial policy

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How to Order a Separate Pen Injector for a Medication Cartridge

Insulin pen devices and pen needles are manufactured and distributed as separate products—you must write a separate prescription for pen needles, as they do not come with the pen injector device. 1

Understanding the Prescription Requirements

The most common prescribing error is assuming the pen comes with needles, which will prevent your patient from using their insulin and represents a critical barrier to therapy initiation. 1 When prescribing an insulin pen system, you need two separate orders:

  • Order #1: The insulin pen device itself (e.g., FlexTouch, KwikPen, SoloStar)
  • Order #2: Compatible pen needles that attach to the pen 1

Specific Needle Specifications to Prescribe

Prescribe 4-mm, 32-gauge pen needles as your first-line choice for all adult patients, including those with obesity. 1 This recommendation is based on evidence showing these needles are safe and effective regardless of BMI and should be inserted perpendicularly at 90 degrees without requiring a skinfold in most adults. 1

Needle Length Options:

  • 4-mm needles: First-line for all patients 1
  • 5-mm needles: Acceptable alternative, though 4-mm is preferred 1
  • 6-mm or longer: Should NOT be prescribed for children due to excessive risk of intramuscular injection 1

Needle Gauge Specifications:

  • 32-gauge (or 31-gauge): Recommended for optimal patient comfort and acceptance 1
  • Thin-walled or extra-thin-walled technology: Preferred as they provide better insulin flow while maintaining a narrow gauge 1

Special Population Considerations

Pediatric Patients:

  • Children and adolescents should use 4-mm needles when possible 1
  • Very young children (≤6 years) must use 4-mm needles with a lifted skinfold and perpendicular insertion 1
  • If using 5-mm or longer needles in children, always inject with a lifted skinfold 1

Very Thin Adults:

  • Adults with BMI <19 should use 4-mm needles with a lifted skinfold and perpendicular insertion 1

Quantity to Prescribe

Consider prescribing needles based on the patient's injection frequency:

  • One needle per injection (needles must be used only once and discarded) 1
  • For a patient injecting 4 times daily: prescribe approximately 120-150 needles per month
  • Account for priming doses when calculating quantity 1

Critical Patient Education Points to Provide

When prescribing pen needles, ensure patients understand:

  • Never reuse needles: They are no longer sterile after a single use 1
  • Remove needles immediately after injection: Do not leave attached to the pen, as air or contaminants can enter the cartridge or medication can leak out 2
  • Prime the pen before each injection: Ensure at least a drop of insulin appears at the needle tip to verify free flow 2
  • Count to 10 before withdrawing: After fully depressing the injection button, wait 10 seconds before removing the needle to ensure complete dose delivery 2, 1
  • Never share pens or needles: Even with a new needle, this can transmit blood-borne infections 1

Common Prescribing Pitfalls to Avoid

  • Failing to prescribe needles separately: This is the single most common error that prevents patients from initiating therapy 1
  • Prescribing needles longer than 6 mm for children: Creates excessive risk of intramuscular injection 1
  • Not specifying needle gauge and length: Generic "pen needle" prescriptions may result in suboptimal needle selection 1
  • Inadequate quantity: Ensure you prescribe enough needles for the patient's injection frequency, remembering that one needle = one injection 1

Compatibility Verification

Ensure the pen needles are ISO-certified compatible with the specific insulin pen device being prescribed. 2 Standard pen needles attach to most modern insulin pens, but verify compatibility with the manufacturer's specifications for the specific pen device. 1

References

Guideline

Insulin Pen Needle Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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