From the Guidelines
Incorporating mevalonic acid into your skin care routine is not recommended as there is no evidence to support its use in skin care, and the provided studies focus on the care of congenital melanocytic nevi in newborns and infants, not on mevalonic acid or its derivatives 1. Instead, to maintain healthy skin, consider the following general skin care tips:
- Bathe with water alone or with a nonsoap cleanser at least 2 to 3 times per week, followed by the application of a bland emollient, as this can help improve skin hydration and skin barrier function 1.
- Apply bland, thick emollients (creams or ointments with minimal or no fragrances or preservatives) for chronic management and low- to mid-potency topical corticosteroids twice daily as needed for acute eczematous flares 1.
- Cleanse ulcerations or erosions with soap or a nonsoap cleanser and water, and apply petroleum jelly or bland ointment and a bandage 1. It's essential to prioritize evidence-based skin care practices and consult with a dermatologist for personalized advice on skin care and any concerns regarding congenital melanocytic nevi or other skin conditions.
From the Research
Incorporating Mevalonic Acid into Skin Care Routine
- Mevalonic acid is an intermediate in cholesterol biosynthesis and has been shown to stimulate de novo cholesterol synthesis and epidermal permeability barrier homeostasis in aged mice 2.
- Topical application of mevalonic acid has been found to enhance barrier recovery in aged mice, accompanied by acceleration of cholesterol synthesis and stimulation of the whole cholesterol biosynthesis 2.
- There is no direct evidence on the best way to incorporate mevalonic acid into a human skin care routine, but it is suggested that topical treatment with mevalonic acid may have beneficial effects on skin health, particularly in aged skin 2.
- A holistic skin care routine that includes cleansing, moisturizing, and photoprotection, in addition to treatment, may be beneficial for overall skin health 3.
- While mevalonic acid is not directly mentioned in the context of a holistic skin care routine, its potential benefits on skin health suggest that it could be a useful ingredient in a comprehensive skin care regimen 2, 3.
Considerations for Skin Care Routine
- Daily skincare routines can have a significant long-term impact on the overall quality of a person's complexion 4.
- A dermatologist-guided holistic skin care routine is essential to improve patient confidence and reduce confusion over product selection 3.
- There is limited research on the use of mevalonic acid in human skin care, and more studies are needed to fully understand its effects and potential benefits 2.
Related Research
- Antioxidants, such as those found in whole foods, may help maintain healthy skin by protecting against photodamage, preventing wrinkles and inflammation, and affecting intracellular signaling pathways involved in skin damage 5.
- Omega-6 and omega-3 polyunsaturated fatty acids have been shown to have beneficial effects on human health, including regulating antioxidant signaling pathways and modulating inflammatory processes 6.