What is the definition and management of lumbar radiculopathy in adults?

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Lumbar Radiculopathy Definition

Lumbar radiculopathy is dysfunction of a lumbar nerve root characterized by pain, sensory impairment, weakness, or diminished deep tendon reflexes in a specific nerve root distribution. 1

Core Clinical Features

The diagnosis requires objective neurological findings, not just pain alone. 2 The American College of Physicians defines radiculopathy as nerve root dysfunction that must include demonstrable deficits such as:

  • Motor weakness in a myotomal distribution 2
  • Sensory deficits in a dermatomal pattern 2
  • Diminished or absent deep tendon reflexes corresponding to the affected nerve root 1, 2
  • Pain radiating in a nerve root distribution 1

Relationship to Sciatica

Sciatica is the most common symptom of lumbar radiculopathy, but they are not synonymous. 1, 2

  • Sciatica describes pain radiating down the leg below the knee in the sciatic nerve distribution, suggesting nerve root compromise from mechanical pressure or inflammation 1
  • A patient can have sciatica without radiculopathy if radiating leg pain exists but objective neurological findings (weakness, sensory loss, reflex changes) are absent 2
  • Conversely, radiculopathy always involves nerve root dysfunction with demonstrable neurological deficits, not just pain 2

Distinction from Plexopathy

Radiculopathy must be distinguished from plexopathy, which involves abnormal symptoms localizing to a nerve plexus rather than a single nerve root. 1 Pain radiating in a dermatomal distribution with accompanying sensory or motor loss reflecting spinal nerve root innervation indicates radiculopathy, whereas plexopathy causes weakness and sensory loss in multiple peripheral nerve territories 1

Specific Nerve Root Examination Findings

The diagnosis requires comprehensive neurological examination targeting specific nerve roots 2:

  • L4 nerve root: Assess knee extension strength and patellar reflex 2
  • L5 nerve root: Test great toe and foot dorsiflexion strength 2
  • S1 nerve root: Evaluate foot plantarflexion and ankle reflexes 2
  • Dermatomal sensory testing in corresponding distributions 2

The combination of radicular pain pattern, dermatomal sensory changes, and motor weakness in a nerve root distribution establishes the diagnosis even without a positive straight leg raise test. 2

Common Pitfall

The straight leg raise test has high sensitivity (91%) but poor specificity (26%) for disc herniation, meaning many positive tests are false positives. 2 Do not rely on this test alone for diagnosis—objective neurological deficits are required 2

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Lumbar Radiculopathy and Sciatica

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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