What is the normal range for arterial pH in a patient with End-Stage Renal Disease (ESRD) on maintenance Hemodialysis (HD)?

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Last updated: February 14, 2025View editorial policy

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From the Research

Arterial pH Range in ESRD Patients on Maintenance Hemodialysis

  • The normal range for arterial pH in patients with End-Stage Renal Disease (ESRD) on maintenance Hemodialysis (HD) is not explicitly stated in the provided studies.
  • However, study 1 reports a mean pH of 7.41 ± 0.03 predialysis and 7.48 ± 0.05 postdialysis in 25 veterans with ESRD receiving outpatient hemodialysis.
  • Study 2 categorizes predialysis pH as <7.30,7.30 to 7.34,7.35 to 7.39, or ≥7.40, and postdialysis pH as <7.40,7.40 to 7.44,7.45 to 7.49, or ≥7.50, but does not provide a specific normal range.
  • Study 3 finds significant differences in pH before and after HD session, but does not provide a specific normal range.
  • Study 4 discusses the importance of acid-base balance in dialysis patients, but does not provide a specific normal range for arterial pH.

Factors Affecting Arterial pH in ESRD Patients on Maintenance Hemodialysis

  • Buffer bicarbonate concentration has a significant effect on bicarbonate concentration after dialysis 3.
  • Predialysis acid-base parameters and post-HD pH are independent of buffer bicarbonate content 3.
  • Serum calcium and albumin levels are associated with pulmonary hypertension severity, which may be related to acid-base balance 5.
  • Predialysis pH ≥7.40 is associated with elevated risk of all-cause and cardiovascular mortality 2.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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