Enteral Feeding Dosage for a 75 kg Patient
For a 75 kg patient requiring enteral nutrition, provide 1,000 mg/day of ribavirin-equivalent calories (approximately 1,500-2,000 kcal/day total energy) with 1.2-1.5 g/kg/day of protein (90-112.5 g/day), delivered via continuous pump feeding starting within 12-24 hours of admission. 1
Energy Requirements
- Target 35-40 kcal/kg/day (2,625-3,000 kcal/day for a 75 kg patient) in postoperative or critically ill patients 1
- For standard medical ICU patients, a minimum of 20 kcal/kg/day (1,500 kcal/day) should be achieved 2
- Energy delivery should cover 1.3x Resting Energy Expenditure, with glucose providing 50-60% of non-protein energy and lipids providing the remainder 3
Protein Requirements
- Deliver 1.2-1.5 g/kg/day of protein (90-112.5 g for a 75 kg patient) 1, 4
- This protein target applies across cirrhosis, liver transplant, and general critical illness populations 1
- In critically ill patients with obesity (BMI 30-40), consider up to 2 g/kg ideal body weight 1
Practical Implementation Protocol
Initiation Timeline
- Start enteral nutrition within 12-24 hours of ICU admission or postoperatively 1
- Do not delay for patients who cannot meet caloric requirements orally 1
Volume Progression
- Increase feeding volume daily by 500 ml 2
- Target maximum of 2,000 ml/day by day 4 of admission 2
- This standardized protocol achieves an 86.2% delivery-to-prescription rate 2
Route Selection
- Begin with gastric feeding via fine-bore nasogastric tube 5
- Check gastric residual volume every 4 hours if gastrointestinal motility is questionable 6
- If GRV exceeds 200 ml, review feeding policy and consider: 6
- Reducing feeding rate
- Adding prokinetic agents (metoclopramide or erythromycin)
- Transitioning to post-pyloric (jejunal) feeding
Formula Selection
- Use standard whole protein formulae as first-line 1
- Consider concentrated high-energy formulae (>1.0 kcal/mL) in patients with ascites for fluid balance 1
- Switch to BCAA-enriched formulae only if hepatic encephalopathy develops during feeding 1
Micronutrient Supplementation
Essential Daily Additions
- Provide water-soluble vitamins and trace elements from day 1 of enteral nutrition 3
- Administer thiamine 100-300 mg/day IV for 3-4 days in ICU patients, particularly those with suspected malnutrition or alcohol use, before starting glucose-containing feeds 1, 7
- Standard enteral formulas at 1,500 kcal/day typically meet micronutrient needs, but patients receiving <1,500 kcal/day require additional supplementation 1
Monitoring Parameters
Clinical Assessment
- Position patient at 30° or more during feeding and for 30 minutes afterward to minimize aspiration risk 6
- Monitor for feeding intolerance signs: vomiting, abdominal distension, reflux into oral cavity 6
- Check blood glucose regularly to detect hypoglycemia and avoid hyperglycemia 3
Laboratory Monitoring
- Monitor phosphate, potassium, and magnesium levels to prevent refeeding syndrome, especially in malnourished patients 3
- Routine vitamin level monitoring is not recommended except for vitamin D 7
Critical Pitfalls to Avoid
Refeeding Syndrome Prevention
- In severely malnourished patients, start cautiously and monitor electrolytes closely 3
- Never administer glucose before thiamine in at-risk patients, as this precipitates Wernicke's encephalopathy 3
Common Feeding Errors
- Avoid interrupting feeds unnecessarily - EN interruptions occur in 32.1% of feeding days and significantly reduce caloric delivery 2
- Do not use PEG placement in cirrhotic patients due to higher complication risk; use nasogastric or nasojejunal tubes instead 1
- Enteral feeding can be safely administered even with esophageal varices present 1
Tolerance Issues
- Post-pyloric feeding becomes necessary in approximately 36% of patients due to high gastric residuals 2
- Delayed achievement of target feeding volume (>4 days) correlates with 73.3% mortality versus 26.1% in those reaching target by day 4 2
Alternative Approach: Permissive Underfeeding
- In select mechanically ventilated patients, permissive underfeeding (50% of daily energy expenditure, approximately 1,300-1,500 kcal/day for 75 kg patient) with maintained protein at 1.2-1.5 g/kg/day produces similar outcomes to full feeding 8
- This approach reduces insulin requirements and improves gastrointestinal tolerance 8
- However, standard full feeding remains the primary recommendation unless specific contraindications exist 1