What are the recommended wound care measures for a stage 2 pressure ulcer?

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Last updated: February 8, 2026View editorial policy

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Wound Care for Stage 2 Pressure Ulcers

Apply hydrocolloid or foam dressings as the primary treatment for stage 2 pressure ulcers, as these dressings are superior to gauze for reducing wound size and promoting healing. 1, 2

Primary Dressing Selection

  • Hydrocolloid dressings are associated with nearly three times more complete healing compared to saline gauze and should be your first-line choice for stage 2 pressure ulcers 1, 3
  • Foam dressings are equally effective as hydrocolloid dressings and may be preferred when moderate to high exudate is present, as they are more absorbent and easier to remove 3
  • Select dressings based on exudate control, comfort, and cost rather than antimicrobial properties, as antimicrobial dressings are not recommended as the sole intervention 1, 2
  • Change hydrocolloid dressings based on clinical need rather than a fixed schedule—typically every 1-7 days depending on exudate levels, with most changes occurring every 1.5-3 days for moderate to heavily exuding wounds 4
  • Extend dressing change intervals to 3-7 days once exudate decreases and healing progresses appropriately 4

Wound Bed Preparation

  • Perform sharp debridement to remove necrotic debris, planktonic bacteria, and biofilm, as this is the critical first step in wound management 4
  • Debride frequently with a scalpel to maintain a clean wound bed and allow accurate assessment of ulcer depth 2
  • Do not perform aggressive debridement if the ulcer is ischemic without signs of infection, as this can worsen tissue damage 1, 2

Pressure Redistribution (Essential Component)

  • Use alternative foam mattresses rather than standard hospital mattresses, which provides a 69% relative risk reduction in pressure ulcer incidence 1, 2
  • Apply support surfaces in all settings including sleeping, seating, and transportation to prevent recurrent injury 4
  • Avoid expensive advanced support surfaces like alternating-air and low-air-loss beds, as evidence for superiority is limited and they add unnecessary costs 1, 2

Nutritional Support

  • Provide protein or amino acid supplementation to reduce wound size, particularly in patients with nutritional deficiencies 4, 1, 2
  • Ensure adequate caloric intake and correct nitrogen balance 1, 2
  • Do not routinely supplement with vitamins or trace elements unless documented deficiency exists, as vitamin C supplementation alone has not shown benefit 4, 1, 2

Adjunctive Therapies to Consider

  • Consider electrical stimulation as adjunctive therapy to accelerate wound healing for stage 2 ulcers, with moderate-quality evidence supporting its use 4, 1, 2
  • Be aware that frail elderly patients may experience more adverse events (primarily skin irritation) with electrical stimulation 2

Infection Management

  • Assess for infection using the NERDS criteria: Nonhealing, Exudate, Red friable tissue, Debris/discoloration, and Smell 4
  • Apply topical antimicrobials (iodine preparations, medical-grade honey, or silver-containing dressings) only when infection is present 4
  • Do not use povidone iodine routinely, as it may impair healing compared to non-antimicrobial dressings 4
  • Obtain wound cultures only when infection is suspected, using quantitative tissue biopsy or semiquantitative swab with Levine technique 4

Critical Pitfalls to Avoid

  • Do not continue standard therapy beyond 4 weeks without considering advanced wound therapy if the ulcer shows inadequate improvement (less than 50% reduction in size) 1, 2
  • Do not neglect vascular assessment when pedal pulses are absent or ulcers fail to improve 1, 2
  • Assess footwear meticulously if the ulcer is on the foot, as ill-fitting shoes are the most frequent cause of ulceration 2
  • Do not culture wounds without clinical signs of infection, as this leads to inappropriate antibiotic use 4

References

Guideline

Treatment of Stage 2 Pressure Ulcers

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Pressure Ulcer Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Management of chronic pressure ulcers: an evidence-based analysis.

Ontario health technology assessment series, 2009

Guideline

Assessment and Treatment of Coccyx Pressure Wounds

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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