From the Guidelines
The management of intestinal candidiasis may be supported by adjunctive supplementation with antifungal agents, including caprylic acid (1000-2000 mg/day) and undecylenic acid (500-1000 mg/day) for 4-6 weeks.
Key Supplements
- Probiotics: Such as Saccharomyces boulardii (500-1000 mg/day) and Lactobacillus acidophilus (1-2 billion CFU/day) may help restore the gut microbiome and prevent candida overgrowth 1.
- Berberine: (500-1000 mg/day) has also been suggested to exhibit antifungal properties, although its efficacy and optimal dosing regimens require further investigation.
- Garlic extract: (600-1200 mg/day) may also exhibit antifungal properties.
Probiotic Strains
Some probiotic strains, such as Saccharomyces boulardii and Lactobacillus acidophilus, have been shown to be effective in reducing the risk of CDAD and improving gut health 1.
Dosage and Duration
The optimal dosage and duration of supplementation with these agents are not well established and may vary depending on individual circumstances.
Important Considerations
It is essential to note that the evidence for the use of these supplements in the management of intestinal candidiasis is not strong, and further research is needed to confirm their efficacy and safety. Additionally, patients should consult with a healthcare professional before starting any supplement regimen.
From the FDA Drug Label
Purpose Antifungal The FDA drug label does not answer the question.
From the Research
Intestinal Candidiasis Treatment
The provided studies do not directly address the best supplements to help fight intestinal candidiasis. However, they discuss various antifungal agents and their uses in treating invasive candidiasis.
Antifungal Agents
- Echinocandins are considered first-line therapy agents for invasive candidiasis 2, 3
- Azoles, such as fluconazole, are also used to treat invasive candidiasis, but resistance is a growing concern 2, 4
- Novel antifungal agents, such as ibrexafungerp and olorofim, are being developed to address the increasing resistance to existing agents 5
- Antifungal stewardship programs are essential to avoid overuse and select the best drug, dose, and duration when needed 4
Treatment Considerations
- The choice of antifungal agent depends on various factors, including the host, site of infection, species of Candida, and its susceptibility profile 3
- Prophylactic antifungal therapy may be appropriate for high-risk patients, such as those with severe immunocompromisation or undergoing certain surgical procedures 6
- Empiric antifungal therapy should be used judiciously, considering the risk of resistance and the lack of robust evidence supporting its use in all surgical procedures 6