Can motion sickness trigger a vasovagal (vasovagal syncope) episode?

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From the Research

Yes, motion sickness can trigger a vasovagal episode in susceptible individuals, as evidenced by the relationship between motion sickness susceptibility and vasovagal syncope susceptibility found in a study published in 2006 1. Motion sickness occurs when there's a mismatch between visual input and vestibular system signals, causing nausea, dizziness, and sweating. These symptoms can activate the vagus nerve, leading to a vasovagal response characterized by a sudden drop in blood pressure and heart rate, potentially resulting in fainting. The most recent and highest quality study on motion sickness, published in 2022 2, highlights the importance of understanding the current concepts and management of motion sickness, including its pathophysiology, physiological and neural mechanisms, individual risk factors, and treatment options. Key points to consider in preventing motion sickness and potential vasovagal episodes include:

  • Taking motion sickness medications like scopolamine, anticholinergics, or antihistamines, as recommended in a study published in 2019 3
  • Using non-pharmaceutical approaches such as sitting in positions with minimal motion, focusing on the horizon, ensuring adequate ventilation, avoiding heavy meals before travel, and using acupressure wristbands
  • Habituation, which remains the most effective nonpharmacological method to reduce motion sickness, as noted in the 2022 study 2 The connection between motion sickness and vasovagal episodes occurs because the autonomic nervous system responds to the distress signals from motion sickness by triggering the parasympathetic response, which can become excessive in some people, leading to decreased blood flow to the brain and syncope. It is essential to consider the individual's susceptibility to motion sickness and vasovagal syncope, as well as their overall health, when developing strategies to prevent and manage these conditions. By prioritizing the most recent and highest quality evidence, we can provide effective recommendations for preventing motion sickness and potential vasovagal episodes, ultimately improving patient outcomes and quality of life.

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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