From the Research
Meloxicam should not be taken continuously for more than 7-10 days without medical supervision, as long-term use increases the risk of serious side effects, and periodic breaks or monitoring may be necessary to minimize these risks. When considering the use of meloxicam for extended periods, it's essential to weigh the benefits against the potential risks, including gastrointestinal bleeding, kidney problems, and cardiovascular events, which increase with duration of use and higher dosages 1.
Some key points to consider when taking meloxicam for longer periods include:
- Regular blood tests to monitor kidney function and other parameters may be recommended by your doctor if long-term therapy is necessary 2
- Alternating with other pain management strategies or medications may help minimize continuous exposure while maintaining symptom control 3
- "Drug holidays" of 1-2 weeks every few months may be considered for patients on chronic therapy, but this should only be done under medical guidance 4
- The gastrointestinal tolerability profile of meloxicam is improved compared to other NSAIDs, such as diclofenac, but it's still crucial to monitor for potential side effects 5
It's also important to note that meloxicam has been shown to be effective in treating osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis, with a COX-2 preferential mechanism of action that may reduce gastrointestinal toxicity 3. However, the potential risks associated with long-term use must be carefully considered and managed by a healthcare provider.