How do I taper off citalopram with only 10mg tablets?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: June 11, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

To taper off citalopram with only 10mg tablets, consult your healthcare provider first, then follow a gradual reduction schedule, such as taking 10mg every other day for 1-2 weeks, then 10mg every third day for 1-2 weeks, before stopping completely, as recommended by recent guidelines 1. When considering tapering off citalopram, it's essential to prioritize a gradual reduction to minimize the risk of withdrawal symptoms, which can include dizziness, nausea, headaches, or mood changes.

  • The tapering process should be individualized and supervised by a healthcare provider to ensure the patient's safety and comfort.
  • A typical tapering schedule may involve reducing the dose by half every 1-2 weeks, but this can be adjusted based on the patient's response and tolerance.
  • It's crucial to maintain regular sleep patterns, exercise moderately, stay hydrated, and continue any therapy during the tapering process to support overall well-being.
  • If withdrawal symptoms become severe, it's essential to contact the doctor immediately to adjust the taper schedule as needed, as abrupt discontinuation can lead to serious complications, including increased risk of overdose or other adverse events 1. Some key considerations when tapering off citalopram include:
  • The importance of gradual reduction to allow the brain chemistry to readjust slowly
  • The need for individualized supervision and support from a healthcare provider
  • The potential for withdrawal symptoms and the importance of monitoring and managing them
  • The importance of maintaining a healthy lifestyle, including regular sleep patterns, exercise, and hydration, during the tapering process.

From the Research

Tapering Off Citalopram with 10mg Tablets

To taper off citalopram with only 10mg tablets, it is essential to understand the importance of gradual tapering to minimize discontinuation symptoms.

  • Gradual tapering is necessary for all serotonin reuptake inhibitors (SRIs), including citalopram, to avoid symptoms such as dizziness, nausea, fatigue, and anxiety 2.
  • A slow hyperbolic tapering of citalopram can mitigate the withdrawal syndrome, but there are no viable dosage forms on the market to implement this tapering scheme 3.
  • Guidelines recommend tapering SSRI treatment over a period of months and down to doses much lower than minimum therapeutic doses to reduce withdrawal symptoms 4.
  • Hyperbolically reducing doses of SSRIs, such as citalopram, can reduce their effect on serotonin transporter inhibition in a linear manner, minimizing withdrawal symptoms 4.

Implementing a Tapering Regimen

When implementing a tapering regimen with 10mg tablets:

  • It is crucial to taper slowly and hyperbolically to minimize withdrawal symptoms 4.
  • Very slow tapering is recommended for all patients, especially those with higher treatment doses and lower clearance of citalopram 5.
  • The tapering regimen should be tailored to the individual patient's needs, taking into account their dosage and treatment history 3.
  • Accurate and personalized doses can be achieved using a tunable modular design approach, which can help reduce the variance in dosing and minimize withdrawal symptoms 3.

Monitoring and Support

During the tapering process:

  • Patients should be closely monitored for withdrawal symptoms, such as dizziness, muscle tension, and confusion 5.
  • Healthcare professionals should be educated about the potential adverse effects of SRI discontinuation to provide proper support and guidance 2.
  • Patients should be reassured that withdrawal symptoms are usually transient, but severe symptoms may require reinstitution of the original dosage or a slower tapering rate 2.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Clinical management of antidepressant discontinuation.

The Journal of clinical psychiatry, 1997

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.