From the Research
Rhodiola rosea supplements may help reduce stress, fatigue, and symptoms of depression, though more research is needed to fully confirm these benefits, as evidenced by a 2022 study 1 that highlighted its effectiveness in alleviating various aspects of life-stress symptoms and stress-induced conditions. The benefits of Rhodiola rosea supplements include:
- Reducing stress and fatigue
- Improving mental performance and cognitive function
- Enhancing physical performance
- Supporting neurotransmitter balance and modulating stress hormones Typical dosages range from 200-600mg daily, standardized to contain 2-3% rosavin and 0.8-1% salidroside, as suggested by a 2010 review 2 that summarized the chemical composition, pharmacological activity, and clinical efficacy of Rhodiola rosea. However, Rhodiola poses risks for certain individuals, particularly those taking prescription medications, such as:
- Interacting with antidepressants (SSRIs, MAOIs), potentially causing serotonin syndrome, as reported in a 2015 case study 3
- Enhancing the effects of blood pressure medications
- Affecting blood sugar levels when taken with diabetes medications
- Interacting with immunosuppressants People with bipolar disorder should avoid Rhodiola as it might trigger manic episodes, and pregnant or breastfeeding women should also avoid it due to insufficient safety data. Before starting Rhodiola, it is essential to consult with a healthcare provider, especially if you have existing health conditions or take medications, to discuss the potential benefits and risks, as well as to determine the appropriate dosage and duration of treatment, as recommended by a 2009 clinical trial 4 that assessed the efficacy of Rhodiola rosea extract in treating stress-related fatigue.