Consensus Definition of Fever
Fever is defined as a rectal temperature greater than 38°C (>100.4°F) according to current medical guidelines. 1
Temperature Measurement Methods
The method of temperature measurement significantly impacts the accuracy of fever detection:
Preferred Methods (in order of reliability)
Core temperature measurements:
- Pulmonary artery catheter thermistors
- Bladder catheter thermistors
- Esophageal balloon thermistors 1
When core measurement devices are not available:
- Rectal temperature (traditional standard)
- Oral temperature (for alert patients) 1
Less reliable methods (avoid when possible):
- Axillary temperatures
- Tympanic membrane temperatures
- Temporal artery thermometers
- Chemical dot thermometers 1
Age-Specific Considerations
Different guidelines provide slightly different thresholds for fever depending on patient population:
- Children under 3 years: Rectal temperature >38°C (>100.4°F) 1
- General hospital-acquired infection: Temperature >38°C (>100.4°F) 1
- ICU patients: Single temperature measurement ≥38.3°C (≥101°F) 1
- Elderly in long-term care:
- Single oral temperature >37.8°C (>100°F)
- Repeated oral temperatures >37.2°C (>99°F)
- Repeated rectal temperatures >37.5°C (>99.5°F)
- Increase from baseline >1.1°C (>2°F) 1
- Neutropenic patients:
- Single oral temperature ≥38.3°C (≥101°F) or
- Temperature ≥38.0°C (≥100.4°F) sustained over at least 1 hour 1
Clinical Implications
Important Considerations
- Normal body temperature varies by 0.5-1.0°C according to circadian rhythm and menstrual cycle 1
- Fever is a normal physiologic response that may help fight infections 1
- Not all infected patients present with fever - some may be euthermic or hypothermic, especially:
- Elderly patients
- Patients with open wounds or burns
- Patients on anti-inflammatory medications
- Patients with certain chronic conditions 1
Special Populations
- Neurological injury: Fever (>37.5°C) should be promptly detected and treated with controlled normothermia (36.0-37.5°C) due to risk of secondary brain injury 1
- Traumatic brain injury: Uncontrolled fever can precipitate secondary brain injury and should be managed aggressively 1
Common Pitfalls to Avoid
Inconsistent temperature measurement methods: Using different methods for the same patient can lead to inconsistent readings and improper fever management.
Overreliance on less accurate methods: Axillary and tympanic measurements can be significantly less accurate than rectal or core temperature measurements.
Failure to recognize fever in high-risk populations: Some patients may have serious infections without fever, especially elderly or immunocompromised individuals.
Lack of standardized definition: The term "fever" is often used without specifying the temperature threshold or measurement method, making it clinically meaningless 2.
Aggressive antipyretic treatment without indication: Fever is a normal adaptive response to infection, and routine suppression with antipyretics may not always be beneficial 3.
The consensus definition of fever as a rectal temperature >38°C (>100.4°F) provides a standardized threshold for clinical practice, though specific populations may require different thresholds based on their unique characteristics and risk factors.